CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8481
Family Name Disintegrin and metalloproteinase domain-containing protein 17 and Disintegrin and metalloproteinase domain-containing protein 17 inhibitor AGN-PC-01NQW6 family
No. of Seeds 44 No. of Other Members 12
Family Centroid CFAMM00387005 Functional Category Bioactive
Superfamily Disintegrin and Retinal dehydrogenase 1 Binder Superfamily
Class Class 1076

Cousin Family NamesSeedsMembers
72 kDa type IV collagenase and Interstitial collagenase Inhibi... 5 81
Serine/threonine-protein kinase PLK1 Inhibitor HMN-214 Family 3 58
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 16
Disintegrin and metalloproteinase domain-containing protein 17... 3 2
Disintegrin and metalloproteinase domain-containing protein 17... 2 1
Disintegrin and metalloproteinase domain-containing protein 17... 2 5
Voltage-dependent L-type calcium channel subunit alpha-1C and ... 3 10
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 15
Matrix metalloproteinase-9 and Interstitial collagenase inhibi... 2 3
Collagenase 3 and 72 kDa type IV collagenase inhibitor N-hydro... 3 25
Disintegrin and metalloproteinase domain-containing protein 17... 1 3
Collagenase 3 and Interstitial collagenase inhibitor (2R,5R)-N... 4 1
Collagenase 3 and A disintegrin and metalloproteinase with thr... 5 6
Translocator protein inhibitor (4S)-N,N-diethyl-9-(2-fluoranyl... 9 10
5-hydroxytryptamine receptor 6 ligand SureCN5253197 family 4 2
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 3 2
Disintegrin and metalloproteinase domain-containing protein 17... 13 3
Disintegrin and metalloproteinase domain-containing protein 17... 16 2
Disintegrin and metalloproteinase domain-containing protein 17... 1 1
Disintegrin and metalloproteinase domain-containing protein 17... 8 0
Neutrophil collagenase and Stromelysin-1 inhibitor (3R)-N-hydr... 2 0
Disintegrin and metalloproteinase domain-containing protein 17... 1 0
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 1 3
Disintegrin and metalloproteinase domain-containing protein 17... 2 1
Disintegrin and metalloproteinase domain-containing protein 17... 3 0
Disintegrin and metalloproteinase domain-containing protein 17... 9 0
Disintegrin and metalloproteinase domain-containing protein 17... 1 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00388320 CHEMBL98202 Bioactive N-hydroxy-N-[1-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonyl-3-(thian-4-ylidene)propan-2-yl]formamide
CFAMM00388326 CHEMBL99995 Bioactive N-hydroxy-N-[1-(4-hydroxyiminocyclohexylidene)-3-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylpropan-2-yl]formamide
CFAMM00388306 CHEMBL318252 Bioactive AGN-PC-074S1L
CFAMM00388312 CHEMBL184942 Bioactive AGN-PC-075EZ3
CFAMM00388318 CHEMBL99365 Bioactive AGN-PC-074S1N
CFAMM00388324 CHEMBL329967 Bioactive AGN-PC-074S1Y
CFAMM00388304 CHEMBL183828 Bioactive N-hydroxy-2-[1-(2-methylpropyl)-3-[[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylmethyl]piperidin-3-yl]acetamide
CFAMM00388310 CHEMBL184200 Bioactive N-hydroxy-2-[1-methyl-2-[[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylmethyl]piperidin-2-yl]acetamide
CFAMM00388316 CHEMBL328645 Bioactive AGN-PC-074S1H
CFAMM00388309 CHEMBL182730 Bioactive N-hydroxy-2-[1-methyl-2-[[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylmethyl]pyrrolidin-2-yl]acetamide
CFAMM00388315 CHEMBL362100 Bioactive AGN-PC-01NQWE
CFAMM00388328 CHEMBL98852 Bioactive AGN-PC-074S1Z
CFAMM00388308 CHEMBL184885 Bioactive AGN-PC-01NQWG
CFAMM00388327 CHEMBL95414 Bioactive AGN-PC-074RWJ
CFAMM00388307 CHEMBL99045 Bioactive AGN-PC-03XHAJ

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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