CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8485
Family Name Dihydrofolate reductase inhibitor 3-(2,4-diamino-6-methylquinazolin-7-yl)-4-ethoxybenzaldehyde family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00220230 Functional Category Bioactive
Superfamily Reverse transcriptase Inhibitor Etravirine Superfamily
Class Class 685

Cousin Family NamesSeedsMembers
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Peptide deformylase, mitochondrial Inhibitor 5-(4-methoxypheno... 5 61
Adenosine receptor A1 and Adenosine receptor A3 Ligand 4-metho... 1 16
Melanin-concentrating hormone receptor 1 Ligand Gnf-pf-2322 Fa... 3 95
Sodium-dependent serotonin transporter Inhibitor 4-furan-2-yl-... 2 10
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 2 3
Cathepsin S and Cathepsin K inhibitor AGN-PC-088VBO family 3 11
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 6 9
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 3 21
Prostaglandin D2 receptor ligand 1-[3-[2-methoxy-6-[2-(4-metho... 6 16
Dihydrofolate reductase inhibitor 7-(3,4-dimethoxyphenyl)-6-me... 1 3
Dihydrofolate reductase inhibitor 7-(5-chloro-2-ethoxyphenyl)-... 2 1
Dihydrofolate reductase inhibitor 7-(2-ethoxynaphthalen-1-yl)-... 3 2
Histamine H4 receptor and Histamine H3 receptor ligand 7-(fura... 2 2
Smoothened homolog and Mitogen-activated protein kinase 14 inh... 7 11
Microsomal triglyceride transfer protein large subunit inhibit... 9 0
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4461871 f... 2 2
Tyrosine-protein kinase ABL1 and Breakpoint cluster region pro... 8 5
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 2 6
Tyrosine-protein kinase Lck inhibitor SureCN374434 family 1 1
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27036 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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