CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8486
Family Name Dihydrofolate reductase inhibitor 7-(5-chloro-2-ethoxyphenyl)-6-methylquinazoline-2,4-diamine family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00220233 Functional Category Bioactive
Superfamily Epidermal growth factor receptor and Receptor tyrosine-protein kinase erbB-2 Binder Superfamily
Class Class 2955

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor Etravirine Family 1 2
Peptide deformylase, mitochondrial Inhibitor 5-(4-methoxypheno... 5 61
Cathepsin S and Cathepsin K inhibitor AGN-PC-088VBO family 3 11
Methionine--tRNA ligase inhibitor 2-[3-[(5-bromo-2-ethoxy-3-me... 9 11
Methionine--tRNA ligase inhibitor SureCN7818675 family 7 14
Fatty-acid amide hydrolase 1 inhibitor (1R)-2-[[6-(3-chloro-4-... 1 4
Dihydrofolate reductase inhibitor 7-(3,4-dimethoxyphenyl)-6-me... 1 3
Dihydrofolate reductase inhibitor 3-(2,4-diamino-6-methylquina... 2 1
Dihydrofolate reductase inhibitor 7-(2-ethoxynaphthalen-1-yl)-... 3 2
Methionine--tRNA ligase inhibitor 2-[3-[(3,5-dibromo-2-ethoxyp... 2 1
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 3 5
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 2 6
1-acyl-sn-glycerol-3-phosphate acyltransferase beta inhibitor ... 1 2
Epidermal growth factor receptor ligand 4-Anilinoquinazoline d... 2 0
1-acyl-sn-glycerol-3-phosphate acyltransferase beta inhibitor ... 1 1
1-acyl-sn-glycerol-3-phosphate acyltransferase beta inhibitor ... 1 0
1-acyl-sn-glycerol-3-phosphate acyltransferase beta inhibitor ... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48711 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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