CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8488
Family Name Melanin-concentrating hormone receptor 1 ligand AGN-PC-075FPC family
No. of Seeds 6 No. of Other Members 1
Family Centroid CFAMM00388350 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 and C-X-C chemokine receptor type 3 Binder Superfamily
Class Class 377

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand monosubstituted indole derivat... 14 475
DNA Binder Primaquine Family 3 245
Alpha-1D adrenergic receptor Ligand Terazosin Family 28 638
Peptide deformylase, mitochondrial Inhibitor Trimetrexate Family 4 311
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Hepatocyte growth factor receptor and Vascular endothelial gro... 28 178
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
Vascular endothelial growth factor receptor 2 Ligand Cediranib... 8 38
Abelson tyrosine-protein kinase 2 and Proto-oncogene tyrosine-... 25 40
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 11 49
Hepatocyte growth factor receptor Ligand Amg 208 Family 20 236
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Platelet-derived growth factor receptor alpha and Platelet-der... 2 9
Alpha-1A adrenergic receptor Ligand RS-17053 Family 9 6
Melanin-concentrating hormone receptor 1 Ligand 8-sec-butoxy-q... 30 39
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
D(2) dopamine receptor Ligand SLV-314 Family 19 69
Epidermal growth factor receptor Ligand 4-(5-bromoindole-3-yl)... 6 15
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 4 32
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
Sodium channel protein type 5 subunit alpha Ligand Enecadin Fa... 1 11
Sigma non-opioid intracellular receptor 1 and Kappa-type opioi... 3 12
Dual specificity mitogen-activated protein kinase kinase 1 inh... 10 54
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 17 69
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 1 15
3-phosphoinositide-dependent protein kinase 1 and Ribosomal pr... 10 4
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 2 3
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 48
Adenosine kinase inhibitor 5-[3-(4-methoxyphenyl)propyl]-6-[2-... 2 11
Aurora kinase A inhibitor AGN-PC-00BCUF family 16 43
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 19 11
Proto-oncogene tyrosine-protein kinase Src inhibitor SureCN525... 8 8
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 8 12
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 3 20
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 6 9
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
Cellular tumor antigen p53 and Lysosomal alpha-glucosidase inh... 1 6
Equilibrative nucleoside transporter 1 inhibitor SureCN9046933... 2 9
Butyrylcholinesterase and Acetylcholinesterase inhibitor AGN-P... 9 24
Serine/threonine-protein kinase Chk2 and Serine/threonine-prot... 1 0
Adenosine receptor A1 and Adenosine receptor A3 ligand AGN-PC-... 6 8
Proto-oncogene tyrosine-protein kinase Src and Vascular endoth... 3 1
Insulin-like growth factor 1 receptor ligand 3qqu family 2 12
Ephrin type-B receptor 4 ligand SureCN5131922 family 4 0
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 1 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 1
Melanin-concentrating hormone receptor 1 ligand N-[3-(2-aminoq... 4 1
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075FSU ... 1 1
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 3 0
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 5 2
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 5 7
Vascular endothelial growth factor receptor 3 and Platelet-der... 8 13
Platelet-derived growth factor receptor beta and Receptor-type... 6 5
Sodium-dependent serotonin transporter and D(2) dopamine recep... 3 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 3
RAC-alpha serine/threonine-protein kinase and cAMP-dependent p... 3 0
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 4 0
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 8 1
Receptor tyrosine-protein kinase erbB-2 and Tyrosine-protein k... 1 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 6
Platelet-derived growth factor receptor alpha and Mast/stem ce... 2 2
Protein-tyrosine kinase 2-beta and Focal adhesion kinase 1 inh... 3 6
Hepatocyte growth factor receptor and Vascular endothelial gro... 15 0
Tyrosine-protein kinase Lck inhibitor AGN-PC-0762WF family 2 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
Tyrosine-protein kinase Lck inhibitor 3-[[2-(benzimidazol-1-yl... 2 0
Histone-lysine N-methyltransferase EHMT2 inhibitor N-(1-cyclop... 1 2
Vascular endothelial growth factor receptor 2 and Cytochrome P... 2 1
Vascular endothelial growth factor receptor 2 and Tyrosine-pro... 4 0
Epidermal growth factor receptor ligand SureCN2989664 family 5 2
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 3 10
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 4 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 23 5
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 6 1
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 1 0
Sodium-dependent serotonin transporter and D(2) dopamine recep... 4 0
Nischarin inhibitor SureCN7810370 family 1 0
Nitric oxide synthase, brain and Nitric oxide synthase, induci... 1 8
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 4 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00388344 CHEMBL359995 Bioactive AGN-PC-075FUR
CFAMM00388351 CHEMBL184080 Bioactive AGN-PC-075FW8
CFAMM00388350 CHEMBL360393 Bioactive AGN-PC-075FPC
CFAMM00388348 CHEMBL362501 Bioactive AGN-PC-075FU0
CFAMM00388347 CHEMBL363909 Bioactive AGN-PC-075FUP
CFAMM00388346 CHEMBL181813 Bioactive AGN-PC-075FSA

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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