CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM849
Family Name Calcitonin gene-related peptide type 1 receptor ligand CHEMBL1092883 family
No. of Seeds 5 No. of Other Members 8
Family Centroid CFAMM00316527 Functional Category Bioactive with Natural Product
Superfamily Gonadotropin-releasing hormone receptor and Beta-lactamase Binder Superfamily
Class Class 173

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
Cholecystokinin receptor type A Ligand Tarazepide Family 6 323
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
Growth hormone receptor Ligand EP-51216 Family 34 390
Histone deacetylase 1 Inhibitor Panobinostat Family 5 93
Lethal factor Inhibitor GM6001 Family 50 435
NF-kappa-B and Protein kinase C zeta type Inhibitor Go6976 Family 9 71
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Somatostatin receptor type 2 Ligand L-054852 Family 13 88
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... 19 64
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[n... 12 10
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... 20 18
Calcitonin gene-related peptide type 1 receptor Ligand Isomer ... 30 31
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 19 108
Endothelin B receptor Ligand IRL-2500 Family 34 87
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Acetylcholinesterase and Cholinesterase Inhibitor 3-(2-diethyl... 12 160
Gonadotropin-releasing hormone receptor ligand 5-[2-[[(2S)-2-[... 7 58
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 17 28
Substance-P receptor ligand N-[(1S,2R)-2-[[(1R)-1-[methyl-(2-p... 2 0
Disintegrin and metalloproteinase domain-containing protein 17... 2 11
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 11 20
Cellular tumor antigen p53 inhibitor CHEMBL1418224 family 1 62
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 0
5-hydroxytryptamine receptor 1A ligand 2-[4-(quinolin-2-ylmeth... 2 91
cGMP-specific 3',5'-cyclic phosphodiesterase and Dual 3',5'-cy... 4 129
Substance-P receptor ligand N-[(2S)-5-[3,5-bis(trifluoromethyl... 4 6
ALK tyrosine kinase receptor and Insulin receptor ligand 9-eth... 9 8
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 3 2
Smoothened homolog inhibitor (8aS)-N-[2-(3-cyanophenyl)pyridin... 3 4
Melanin-concentrating hormone receptor 2 ligand N-[(1R)-1'-(9H... 4 1
Poly [ADP-ribose] polymerase 1 inhibitor CHEMBL1935258 family 7 2
Adenosine receptor A2b and Adenosine receptor A2a ligand N-(4-... 2 14
Oxytocin receptor ligand (3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)... 20 2
Cathepsin K and Cathepsin B inhibitor (1R,2R)-N-(1-cyanocyclop... 10 7
Serine/threonine-protein kinase Chk1 inhibitor SureCN5547533 f... 3 2
Translocator protein inhibitor CHEMBL2331870 family 2 0
Disintegrin and metalloproteinase domain-containing protein 17... 7 9
Gonadotropin-releasing hormone receptor ligand SureCN7899418 f... 12 4
Orexin receptor type 2 and Orexin receptor type 1 ligand SureC... 2 0
Phospholipase D1 and Phospholipase D2 inhibitor SureCN10311349... 2 14
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 3 5
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 3 8
Calcitonin gene-related peptide type 1 receptor ligand N-[(2R)... 1 0
Angiopoietin-1 receptor and Vascular endothelial growth factor... 1 0
Somatostatin receptor type 4 and Somatostatin receptor type 5 ... 3 4
5-hydroxytryptamine receptor 7 ligand AGN-PC-00PFK0 family 1 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL3... 1 9


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00316524 CHEMBL1269977 Bioactive AGN-PC-09M9LN
CFAMM00316530 CHEMBL1090848 Bioactive CHEMBL1090848
CFAMM00316529 CHEMBL1090846 Bioactive (7S)-1'-methyl-2-[(2-oxo-3,4-dihydroquinolin-1-yl)methyl]spiro[6,8-dihydrocyclopenta[g]quinoline-7,5'-imidazolidine]-2',4'-dione
CFAMM00316534 CHEMBL1090841 Bioactive CHEMBL1090841
CFAMM00316527 CHEMBL1092883 Bioactive CHEMBL1092883

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27264 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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