CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name C-C chemokine receptor type 2 ligand SureCN2988733 family
No. of Seeds 14 No. of Other Members 17
Family Centroid CFAMM00316559 Functional Category Bioactive
Superfamily C-C chemokine receptor type 5 Ligand AZD5672 Superfamily
Class Class 905

Cousin Family NamesSeedsMembers
Cathepsin K Inhibitor Odanacatib Family 33 84
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Potassium voltage-gated channel subfamily A member 5 Ligand N-... 8 32
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 3 21
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
C-C chemokine receptor type 2 ligand SureCN2983871 family 9 8
Cathepsin K and Cathepsin L1 inhibitor N-[1-(cyanomethylcarbam... 2 0
C-C chemokine receptor type 2 ligand 2-(cyclohexanecarbonylami... 1 0
C-C chemokine receptor type 2 ligand AGN-PC-03L0X5 family 13 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 5
Neutrophil elastase inhibitor 1-[(2S)-3-methyl-2-[(4-methylsul... 3 0
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[ethyl-[2-(4... 1 1
C-C chemokine receptor type 2 ligand AGN-PC-03L0Z6 family 1 1
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2J2 inhib... 5 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor N-... 1 0


External ID

Functional Category

Molecule Name

CFAMM00316537 CHEMBL496630 Bioactive SureCN2989443
CFAMM00316536 CHEMBL502516 Bioactive SureCN2998305
CFAMM00316562 CHEMBL1092941 Bioactive SureCN4416855
CFAMM00316555 CHEMBL1946830 Bioactive N-[2-[[(1S,2R,4R)-2-(benzenesulfonylmethyl)-4-(propan-2-ylamino)cyclohexyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamide
CFAMM00316535 CHEMBL496432 Bioactive SureCN2985948
CFAMM00316561 CHEMBL1091604 Bioactive N-[2-[[(1S,2R,4R)-2-(benzenesulfonylmethyl)-4-[methyl(propan-2-yl)amino]cyclohexyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamide
CFAMM00316560 CHEMBL1091605 Bioactive SureCN4421729
CFAMM00316559 CHEMBL497202 Bioactive SureCN2988733
CFAMM00316539 CHEMBL1092678 Bioactive SureCN4417196
CFAMM00316552 CHEMBL1092748 Bioactive N-[(3S)-1-[(1S,2R,4R)-2-(benzenesulfonylmethyl)-4-[methyl(propan-2-yl)amino]cyclohexyl]-2-oxopyrrolidin-3-yl]-3,5-bis(trifluoromethyl)benzamide
CFAMM00316558 CHEMBL502247 Bioactive SureCN2983131
CFAMM00316538 CHEMBL1090893 Bioactive SureCN4416761
CFAMM00316551 CHEMBL502793 Bioactive SureCN2983508
CFAMM00316544 CHEMBL451340 Bioactive SureCN2987271

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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