CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8508
Family Name Sodium-dependent serotonin transporter and Sodium-dependent noradrenaline transporter inhibitor (1S,6R)-1-(3,4-dichlorophenyl)-6-(pyrrol-1-ylmethyl)-4-azabicyclo[4.1.0]heptane family
No. of Seeds 5 No. of Other Members 3
Family Centroid CFAMM00388414 Functional Category Bioactive
Superfamily Sodium-dependent serotonin transporter and Sodium-dependent noradrenaline transporter Binder Superfamily
Class Class 3476

Cousin Family NamesSeedsMembers
Glutamate dehydrogenase inhibitor quinoline derivative Chloroq... 7 189
Histamine H1 receptor ligand tricyclic antidepressant Deslorat... 6 136
D(2) dopamine receptor Ligand Sertindole Family 3 173
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor Ethion... 5 68
D(1B) dopamine receptor Ligand LE-300 Family 65 452
ABC294640 family 5 75
Nicotinic acetylcholine receptor Ligand Epibatidine Family 36 19
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 6 48
D(2) dopamine receptor and D(3) dopamine receptor Ligand L-741... 9 73
Potassium voltage-gated channel subfamily H member 2 Ligand 5-... 5 14
5-hydroxytryptamine receptor 2A Ligand 8-chloro-1,2,3,4-tetrah... 5 4
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 2 11
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 13 26
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Cytochrome P450 11B1, mitochondrial Inhibitor 2-methyl-1,2-di-... 8 15
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 3-chlo... 3 2
Metabotropic glutamate receptor 5 Ligand 5-((6-methylpyridin-2... 14 22
D(4) dopamine receptor and D(1A) dopamine receptor ligand 2-[[... 5 4
Melatonin receptor type 1A and Melatonin receptor type 1C liga... 2 5
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 9 3
Sodium-dependent serotonin transporter and Sodium-dependent no... 14 6
5-hydroxytryptamine receptor 6 ligand 9-(2-bromophenyl)sulfony... 2 0
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 8 0
D(4) dopamine receptor and D(1A) dopamine receptor ligand AGN-... 1 0
Nitric oxide synthase, brain and Nitric oxide synthase, induci... 2 0
Glucagon receptor and Mitogen-activated protein kinase 14 liga... 1 1
Sodium/hydrogen exchanger 1 inhibitor 2-[(E)-[7-(2,3-dichlorop... 1 1
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42686 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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