CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8526
Family Name B1 bradykinin receptor ligand AGN-PC-005XAO family
No. of Seeds 3 No. of Other Members 17
Family Centroid CFAMM00388540 Functional Category Bioactive
Superfamily Thromboxane A2 receptor Ligand Bibv 308 Superfamily
Class Class 960

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Prothrombin Inhibitor Ximelegatran Family 8 157
Thromboxane A2 receptor Ligand Bibv 308 Family 14 40
JAK Inhibitor Momelotinib Family 33 83
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
XL-888 family 16 85
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Cyclin-dependent kinase 4 Inhibitor 1-(9-oxo-9h-fluoren-4-yl)-... 3 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Hydroxycarboxylic acid receptor 2 Ligand 2-(6-phenylhexyl)pyri... 4 11
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... 2 11
Hydroxycarboxylic acid receptor 2 ligand AGN-PC-07ZGMC family 3 22
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Integrin beta-3 and Integrin alpha-V inhibitor SureCN547914 fa... 8 32
Integrin alpha-V and Integrin beta-5 inhibitor SureCN6563167 f... 2 10
ALK tyrosine kinase receptor ligand SureCN1600195 family 1 1
Integrin beta-3 and Integrin alpha-V inhibitor (3R)-3-quinolin... 6 8
Prothrombin and Cationic trypsin inhibitor tert-butyl N-[(2R)-... 4 3
Mitogen-activated protein kinase 1 and Cytochrome P450 3A4 inh... 1 0
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-[[2-[6-m... 13 12
Integrin beta-3 and Integrin alpha-V inhibitor SureCN6359092 f... 9 5
Renin inhibitor (3R)-4-[[(2S,5S)-1-cyclohexyl-3-hydroxy-6-meth... 3 4
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-0733AC family 7 29
Mast/stem cell growth factor receptor Kit and Mitogen-activate... 4 2
Protein kinase C theta type and Leucine-rich repeat serine/thr... 1 1
Neuropeptide Y receptor type 5 ligand AGN-PC-07R6YQ family 7 7
Neuropeptide Y receptor type 5 ligand SureCN4170426 family 4 13
B1 bradykinin receptor ligand methyl 2-fluoro-6-[3-fluoro-4-[[... 22 11
Substance-P receptor ligand Netupitant family 5 2
Lysine--tRNA ligase inhibitor 4-[[2-(2-piperazin-1-ylpyridin-4... 2 0
Aurora kinase A and Aurora kinase B inhibitor 4-fluoro-N-[4-[(... 6 1
B1 bradykinin receptor ligand methyl 2-[4-[(1R)-1-[[3-[(2-cyan... 8 7
Melanin-concentrating hormone receptor 1 ligand 6-(4-chlorophe... 8 1
C-C chemokine receptor type 5 ligand AC1MHRXO family 5 1
B1 bradykinin receptor ligand N-[4-chloro-2-[[(1R)-1-[4-[3-flu... 5 5
Bone morphogenetic protein 1 inhibitor (3R)-6-cyclohexyl-N-hyd... 3 7
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-00IW9E f... 3 0
Integrin alpha-V and Integrin beta-6 inhibitor 3-[[2-[4-[(4-me... 4 3
B1 bradykinin receptor ligand N-[2-[[4-(2-chlorophenyl)-4-cyan... 2 0
Coagulation factor VII inhibitor 2-[2-[(1-aminoisoquinolin-6-y... 1 14
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(3-fluor... 10 0
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-074ASZ f... 5 0
Fatty-acid amide hydrolase 1 inhibitor AGN-PC-04UH3X family 5 2
Macrophage colony-stimulating factor 1 receptor ligand N-[3-[(... 5 0
Transient receptor potential cation channel subfamily V member... 3 2
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
Bifunctional epoxide hydrolase 2 and Potassium voltage-gated c... 1 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand N-[(2... 3 1
Integrin beta-1 and Integrin alpha-5 inhibitor 2-[(2,6-dimethy... 9 1
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-3-[4-[4-[[... 2 0
Sigma non-opioid intracellular receptor 1 ligand methyl 1-(4-c... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00388553 CHEMBL182275 Bioactive methyl 2-[4-[[[3-[(2-cyanoacetyl)amino]-4-methylpyridin-2-yl]amino]methyl]phenyl]cyclohexane-1-carboxylate
CFAMM00388548 CHEMBL181961 Bioactive 2-cyano-N-[4-methyl-2-[[4-[(1S,6S)-6-(3-methyl-1,2,4-oxadiazol-5-yl)cyclohex-3-en-1-yl]phenyl]methylamino]pyridin-3-yl]acetamide
CFAMM00388540 CHEMBL182378 Bioactive AGN-PC-005XAO

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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