CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8527
Family Name Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[4-chloro-3-[[2-methyl-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]phenyl]acetic acid family
No. of Seeds 15 No. of Other Members 5
Family Centroid CFAMM00388560 Functional Category Bioactive
Superfamily Prostaglandin D2 receptor and Prostacyclin receptor Binder Superfamily
Class Class 648

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor Liga... 17 31
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Leukotriene A-4 hydrolase Inhibitor N5-[4-(2-oxo-3-phenylpropo... 1 61
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 8 39
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 49 8
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 4 2
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Integrin beta-1 and Integrin alpha-4 inhibitor 3-[4-[(2,6-dich... 5 6
Androgen receptor ligand (2R)-2-ethyl-1-(2,2,2-trifluoroethyl)... 32 6
Prostaglandin D2 receptor ligand 2-[4-chloro-3-[[4-[[(3R)-2,3-... 2 0
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 18 2
Prostaglandin D2 receptor 2 ligand 2-[4-methoxy-3-[2-[[(1S)-1-... 5 28
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 9 3
Mitogen-activated protein kinase 14 inhibitor Skepinone-L family 11 31
Mitogen-activated protein kinase 14 inhibitor N-[2,4-difluoro-... 4 1
Mitogen-activated protein kinase 14 inhibitor N-[2-fluoro-5-[(... 4 5
Integrin beta-3 and Integrin alpha-2 inhibitor 3-(4-methoxyphe... 4 6
Integrin alpha-4 inhibitor SureCN14558473 family 7 4
Integrin alpha-4 inhibitor SureCN14558471 family 16 2
Glucagon receptor and Adenylate cyclase type 1 ligand AGN-PC-0... 3 1
Prostaglandin D2 receptor 2 ligand AGN-PC-07CQC5 family 4 0
Mitogen-activated protein kinase 14 inhibitor AGN-PC-00A4QT fa... 2 0
Mitogen-activated protein kinase 14 inhibitor ITX 5061 free ba... 2 3
Mitogen-activated protein kinase 14 inhibitor AGN-PC-04UTCQ fa... 2 1
Leukotriene B4 receptor 1 ligand 4-methoxy-3-[[(E)-3-(4-phenyl... 2 10
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 2 0
Mitogen-activated protein kinase 14 inhibitor SureCN1600485 fa... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00388558 CHEMBL1915677 Bioactive 2-[4-chloro-3-[[2,5-dimethyl-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]phenyl]acetic acid
CFAMM00388570 CHEMBL1819620 Bioactive 2-[3-[[2-chloro-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]-5-methylphenyl]acetic acid
CFAMM00388563 CHEMBL1819617 Bioactive 2-[2-fluoro-5-[[2-methyl-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]phenyl]acetic acid
CFAMM00388556 CHEMBL1915856 Bioactive 2-[4-chloro-3-[[2,6-dimethyl-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]phenyl]acetic acid
CFAMM00388569 CHEMBL1819621 Bioactive 2-[5-[[2-chloro-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]-2-methylphenyl]acetic acid
CFAMM00388562 CHEMBL1819616 Bioactive 2-[3-fluoro-5-[[2-methyl-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]phenyl]acetic acid
CFAMM00388561 CHEMBL1819615 Bioactive 2-[4-fluoro-3-[[2-methyl-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]phenyl]acetic acid
CFAMM00388567 CHEMBL1915865 Bioactive 1-[4-chloro-3-[[2,6-dimethyl-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]phenyl]cyclopropane-1-carboxylic acid
CFAMM00388560 CHEMBL1819614 Bioactive 2-[4-chloro-3-[[2-methyl-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]phenyl]acetic acid
CFAMM00388566 CHEMBL1915863 Bioactive 2-[4-chloro-3-[[2,6-dimethyl-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]phenyl]-2-methylpropanoic acid
CFAMM00388559 CHEMBL1819619 Bioactive 2-[3-[[2-chloro-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]-4-methylphenyl]acetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45128 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543