CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8528
Family Name Pol polyprotein inhibitor Lysine Sulfonamide 6h family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00388571 Functional Category Bioactive
Superfamily Integrin beta-3 and Pol polyprotein Binder Superfamily
Class Class 3320

Cousin Family NamesSeedsMembers
Solute carrier family 12 member 1 Inhibitor Torasemide Family 13 75
Thromboxane A2 receptor Ligand Bibv 308 Family 14 40
Potassium-competitive acid Inhibitor TAK-438 Family 2 8
Thromboxane-A synthase Inhibitor CGS-22652 Family 37 95
Thromboxane A2 receptor and Thromboxane-A synthase ligand AGN-... 4 19
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 19 53
Thromboxane-A synthase and Thromboxane A2 receptor ligand (E)-... 2 1
Thromboxane A2 receptor and Thromboxane-A synthase ligand 3-[(... 3 0
Pol polyprotein inhibitor AGN-PC-0AAOIM family 4 0
Thromboxane A2 receptor and Thromboxane-A synthase ligand (E)-... 2 0
Thromboxane-A synthase and Thromboxane A2 receptor ligand (E)-... 3 0
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-2-(benzene... 3 2
Pol polyprotein inhibitor AC1LAHQ9 family 8 15
Nicotinamide phosphoribosyltransferase inhibitor 1-[4-(8-oxa-3... 5 4
Integrin beta-1 and Integrin alpha-5 inhibitor 2-[(2,6-dimethy... 9 1
Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1-(4-methylphenyl)sul... 1 1


External ID

Functional Category

Molecule Name

CFAMM00388571 CHEMBL181972 Bioactive Lysine Sulfonamide 6h

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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