CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8533
Family Name Prothrombin inhibitor SureCN6921523 family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00388585 Functional Category Bioactive
Superfamily Vasopressin V1a receptor and Prothrombin Binder Superfamily
Class Class 3498

Cousin Family NamesSeedsMembers
Substance-K receptor and Substance-P receptor Ligand DNK-333 F... 15 95
Prothrombin Inhibitor D-leucyl-n-(3-chlorobenzyl)-l-prolinamid... 18 168
Dipeptidyl peptidase 4 Inhibitor N4-(4-chlorobenzyl)-2,4-diami... 10 22
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
Aminopeptidase N Inhibitor N1-(4-chlorobenzyl)-2-benzyl-n3-hyd... 9 86
Prothrombin inhibitor (2S)-N-[[2-(aminomethyl)-5-chlorophenyl]... 5 11
P2X purinoceptor 7 inhibitor (4S)-N-[(2,4-dichlorophenyl)methy... 16 11
Prothrombin inhibitor SureCN6924249 family 6 4
Melanocortin receptor 4 and Melanocortin receptor 5 ligand (3R... 6 1
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 8 4
P2X purinoceptor 7 inhibitor (2S)-N-[[2-chloro-3-(trifluoromet... 3 0
Prothrombin inhibitor (2S)-1-[(2R)-2-amino-2-cyclohexylacetyl]... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00388585 CHEMBL182997 Bioactive SureCN6921523
CFAMM00388583 CHEMBL361593 Bioactive SureCN6926518
CFAMM00388582 CHEMBL182124 Bioactive (2S)-N-[[2-(aminomethyl)-5-chlorophenyl]methyl]-1-[(2R)-3-cyclopropyl-2-hydroxy-3-methylbutanoyl]azetidine-2-carboxamide
CFAMM00388581 CHEMBL361432 Bioactive (2S)-N-[[2-(aminomethyl)-5-chlorophenyl]methyl]-1-[(2R)-2-hydroxy-3,3-dimethylbutanoyl]azetidine-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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