CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8543
Family Name Hepatocyte growth factor receptor ligand 5-[(2,6-dichlorophenyl)methylsulfonyl]-3-[(Z)-[3,5-dimethyl-4-[2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carbonyl]-1,3-dihydropyrrol-2-ylidene]methyl]indol-2-one family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00388687 Functional Category Bioactive
Superfamily Beta-lactamase and Nonstructural protein 1 Binder Superfamily 10
Class Class 289

Cousin Family NamesSeedsMembers
Hepatocyte growth factor receptor and Protein-tyrosine kinase ... 2 15


External ID

Functional Category

Molecule Name

CFAMM00388686 CHEMBL450786 Bioactive PHA-665752
CFAMM00388687 CHEMBL1822004 Bioactive 5-[(2,6-dichlorophenyl)methylsulfonyl]-3-[(Z)-[3,5-dimethyl-4-[2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carbonyl]-1,3-dihydropyrrol-2-ylidene]methyl]indol-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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