CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8546
Family Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform and Serine/threonine-protein kinase mTOR inhibitor N-[6-[6-chloro-5-[(4-fluorophenyl)sulfonylamino]pyridin-3-yl]-1H-benzimidazol-2-yl]acetamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00375734 Functional Category Bioactive
Superfamily Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform and Serine/threonine-protein kinase mTOR Binder Superfamily
Class Class 853

Cousin Family NamesSeedsMembers
Interleukin-1 receptor type 1 and Mitogen-activated protein ki... 7 151
Arachidonate 5-lipoxygenase Inhibitor 2,4,5-triarylimidazole A... 3 16
NF-kappa-B Inhibitor 9-chloro-5h-6-thia-4,5-diaza-chrysene 6,6... 3 27
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 13 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 13 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 0
Mitogen-activated protein kinase 14 inhibitor 6-[5-(2,4-difluo... 9 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 8
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 15 3
Cyclin-dependent kinase 1 inhibitor 4-[[4-(3H-benzimidazol-5-y... 1 0
High affinity nerve growth factor receptor ligand N-[3-amino-5... 4 10
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 5 0
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 2 3
5-hydroxytryptamine receptor 2B ligand SureCN1299053 family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27759 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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