CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8572
Family Name Aurora kinase B and Aurora kinase A inhibitor 2-[(3S,4S)-3-(2-fluorophenoxy)-4-hydroxypyrrolidin-1-yl]-N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]acetamide family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00388879 Functional Category Bioactive
Superfamily Aurora kinase A and Aurora kinase B Binder Superfamily 3
Class Class 935

Cousin Family NamesSeedsMembers
Tyrosine-protein kinase Lck and Aurora kinase B Inhibitor VX-6... 28 56
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
Aurora kinase B and Aurora kinase A inhibitor 2-[(3S,4S)-3-hyd... 22 5
Aurora kinase B and Aurora kinase A inhibitor AGN-PC-09QXA7 fa... 16 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00388879 CHEMBL1822656 Bioactive 2-[(3S,4S)-3-(2-fluorophenoxy)-4-hydroxypyrrolidin-1-yl]-N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]acetamide
CFAMM00388878 CHEMBL1822661 Bioactive 2-[(3S,4R)-3-(4-fluorophenoxy)-4-hydroxypyrrolidin-1-yl]-N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26223 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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