CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8577
Family Name Hepatocyte growth factor receptor ligand [3,5-dichloro-4-[4-(3-chlorophenyl)-5-[2-[4-[2-(diethylamino)ethoxy]anilino]pyrimidin-4-yl]-1H-imidazol-2-yl]phenyl]methanol family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00388929 Functional Category Bioactive
Superfamily Beta-secretase 1 and Amyloid beta A4 protein Binder Superfamily
Class Class 2014

Cousin Family NamesSeedsMembers
Receptor tyrosine-protein kinase erbB-2 Inhibitor TAK-285 Family 16 124
Peptide deformylase, mitochondrial Inhibitor Epiroprim Family 5 68
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor Su... 2 16
Renin inhibitor AGN-PC-09M4GD family 3 4
Cellular tumor antigen p53 and Lysosomal alpha-glucosidase inh... 1 6
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 2 4
Receptor tyrosine-protein kinase erbB-2 ligand 2-[2-[4-[3-chlo... 4 5
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 3 0
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 3 14
Glucagon receptor ligand SureCN2647807 family 3 7
Fibroblast growth factor receptor 1 and Proto-oncogene tyrosin... 2 0
Beta-secretase 1 and Amyloid beta A4 protein inhibitor SureCN3... 1 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00388929 CHEMBL1822790 Bioactive [3,5-dichloro-4-[4-(3-chlorophenyl)-5-[2-[4-[2-(diethylamino)ethoxy]anilino]pyrimidin-4-yl]-1H-imidazol-2-yl]phenyl]methanol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27261 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543