CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8579
Family Name 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 7 ligand N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-2,5-dimethyl-1-phenylimidazole-4-carboxamide;hydrochloride family
No. of Seeds 3 No. of Other Members 13
Family Centroid CFAMM00380228 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 2A and Sodium-dependent serotonin transporter Binder Superfamily 2
Class Class 1027

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Adenosine receptor A3 Ligand 2-(5-chloro-1h-benzo[d]imidazol-2... 7 51
Cannabinoid receptor 1 Ligand 1-(4-chlorophenyl)-2-(2,4-dichlo... 18 41
Adenosine receptor A1 ligand SureCN10614388 family 5 1
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 7 7
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor Su... 16 5
Melanin-concentrating hormone receptor 1 and Potassium voltage... 8 27
Lysosomal Pro-X carboxypeptidase inhibitor 2-amino-N-[(2S)-1-[... 11 16
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 18
Lysosomal Pro-X carboxypeptidase inhibitor N-[(1S)-1-(5,6-dich... 3 21
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 14
Metabotropic glutamate receptor 5 ligand SureCN3866791 family 2 10
5-hydroxytryptamine receptor 2A and Sodium-dependent serotonin... 3 14
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 10 14
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 8
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 1 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 5 4
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 5
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 5 0
Tyrosine-protein kinase Lck and Proto-oncogene tyrosine-protei... 3 0
Adenosine receptor A2b ligand N-(4-chlorophenyl)-2-[(5Z)-5-(2,... 1 2
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 2 0
Platelet-derived growth factor receptor beta and Fibroblast gr... 10 0
Sonic hedgehog protein and Cytochrome P450 2C9 inhibitor AGN-P... 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 9 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 1
Centromere-associated protein E inhibitor 5-bromo-N-[(3,4-dich... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00388947 CHEMBL2346726 Bioactive 1-(3,4-dichlorophenyl)-2,5-dimethyl-N-(6-methylpyridin-2-yl)imidazole-4-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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