CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8586
Family Name Histamine H3 receptor and Potassium voltage-gated channel subfamily H member 2 ligand 4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]-N-propylbenzenesulfonamide family
No. of Seeds 6 No. of Other Members 3
Family Centroid CFAMM00388984 Functional Category Bioactive
Superfamily Histamine H3 receptor and Corticosteroid 11-beta-dehydrogenase isozyme 1 Binder Superfamily
Class Class 2606

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 7 and D(2) dopamine receptor Liga... 3 29
Alpha-2A adrenergic receptor Ligand SK&F-29661 Family 3 42
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Oxytocin receptor and Vasopressin V1a receptor Ligand 1'-tosyl... 1 7
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 6 7
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 8 10
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 34
C-C chemokine receptor type 5 ligand methyl N-[1-[(3S)-4-[benz... 3 18
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 6
Histamine H3 receptor ligand 2-[4-[4-[2-[(2R)-2-methylpyrrolid... 4 11
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 3
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 6 4
Histamine H3 receptor and Potassium voltage-gated channel subf... 4 0
Histamine H3 receptor and Potassium voltage-gated channel subf... 14 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 10
Tryptase alpha/beta-1 inhibitor N-[2-[3-[4-(aminomethyl)phenyl... 1 0
Neuropeptide Y receptor type 5 and Neuropeptide Y receptor typ... 1 5
Histamine H3 receptor and Potassium voltage-gated channel subf... 5 0
Histamine H3 receptor ligand N,N-diethyl-4-[4-[2-[(2R)-2-methy... 4 0
Neuropeptide Y receptor type 5 ligand AGN-PC-0A7RNK family 2 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00388988 CHEMBL563696 Bioactive 3-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]-N-propan-2-ylbenzenesulfonamide
CFAMM00388987 CHEMBL569832 Bioactive SureCN14310574
CFAMM00388985 CHEMBL558260 Bioactive N-(cyclopropylmethyl)-4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]benzenesulfonamide
CFAMM00388991 CHEMBL550198 Bioactive 4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]-N-propan-2-ylbenzenesulfonamide
CFAMM00388984 CHEMBL1823051 Bioactive 4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]-N-propylbenzenesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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