CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8595
Family Name Prothrombin inhibitor SureCN6924249 family
No. of Seeds 6 No. of Other Members 4
Family Centroid CFAMM00389034 Functional Category Bioactive
Superfamily Muscarinic acetylcholine receptor M1 and Muscarinic acetylcholine receptor M3 Binder Superfamily 7
Class Class 3243

Cousin Family NamesSeedsMembers
C-C chemokine receptor type 5 ligand 1-[1-[[(3S,4R)-1-(cyclope... 7 13
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 10 20
Prothrombin inhibitor SureCN6921523 family 4 1
C-C chemokine receptor type 1 ligand N-[(2R)-1-[(4S)-4-(4-chlo... 15 6
C-C chemokine receptor type 1 ligand 4-chloro-N-[(2R)-1-[(4S)-... 6 3
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 0
Prothrombin and Trypsin-1 inhibitor L-372460 family 1 0
Prothrombin inhibitor (2S)-1-[(2R)-2-amino-2-cyclohexylacetyl]... 2 1


External ID

Functional Category

Molecule Name

CFAMM00389043 CHEMBL190075 Bioactive SureCN6921055
CFAMM00389041 CHEMBL362206 Bioactive SureCN6926513
CFAMM00389034 CHEMBL191062 Bioactive SureCN6924249
CFAMM00389040 CHEMBL184580 Bioactive (2S)-N-[[2-(aminomethyl)-5-chlorophenyl]methyl]-1-[(2R)-2-hydroxy-2-phenylacetyl]pyrrolidine-2-carboxamide
CFAMM00389037 CHEMBL193188 Bioactive (2S)-N-[[2-(2-aminoethyl)-5-chlorophenyl]methyl]-1-(9-hydroxyfluorene-9-carbonyl)pyrrolidine-2-carboxamide
CFAMM00389036 CHEMBL182320 Bioactive (2S)-N-[[2-(aminomethyl)-5-chlorophenyl]methyl]-1-[(2R)-2-hydroxy-2-phenylpropanoyl]pyrrolidine-2-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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