CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM860
Family Name Sodium-dependent dopamine transporter and Sodium-dependent serotonin transporter inhibitor 3-(4-{2-[bis(4-fluorophenyl)methoxy]ethyl}piperazin-1-yl)-1-(4-bromophenyl)propan-1-ol family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00237349 Functional Category Bioactive
Superfamily Sodium-dependent dopamine transporter and Sodium-dependent serotonin transporter Binder Superfamily 2
Class Class 3240

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Diphenhydramine Family 5 75
Alpha-1B adrenergic receptor ligand Morpholine derivative Phen... 4 152
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
Muscarinic acetylcholine receptor Ligand Umeclidinium Family 7 50
Choline kinase alpha Inhibitor Hemicholinium-3 Family 4 0
Substance-P receptor Ligand L-733060 Family 19 71
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 3 1
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 11 3
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
Sodium-dependent dopamine transporter and Sodium-dependent nor... 5 2
Sodium-dependent dopamine transporter and Sodium-dependent nor... 4 19
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 2 11
Sigma non-opioid intracellular receptor 1 ligand 2-[(3R)-1'-(c... 2 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 6 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 0
Sodium-dependent dopamine transporter and Transporter inhibito... 2 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 0
Substance-P receptor ligand SureCN8415737 family 3 4
Sodium-dependent serotonin transporter and Sodium-dependent do... 3 0
Sodium-dependent dopamine transporter and Transporter inhibito... 2 0
Sigma non-opioid intracellular receptor 1 and Vesicular acetyl... 1 4
Sodium-dependent dopamine transporter and Sigma non-opioid int... 2 0
Histamine H1 receptor and 5-hydroxytryptamine receptor 2A liga... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27276 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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