CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8610
Family Name Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 inhibitor 4-Acylamino-6-arylfuro[2,3-d]pyrimidine 24 family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00223809 Functional Category Bioactive
Superfamily MK-6096 Superfamily
Class Class 1305

Cousin Family NamesSeedsMembers
Metabotropic glutamate receptor 1 Ligand PF-1913539 Family 130 817
Serine/threonine-protein kinase mTOR Inhibitor INK128 Family 2 15
MK-6096 family 3 69
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 7 37
Serine/threonine-protein kinase Chk1 Inhibitor N-(5,6-diphenyl... 9 100
Adenosine receptor A1 and Adenosine receptor A2a Ligand 4-(fur... 7 15
5-hydroxytryptamine receptor 2C Ligand 6-methyl-4-(piperazin-1... 1 0
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 1 0
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Neuropeptide Y receptor type 5 ligand SureCN5771669 family 2 3
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 1
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 2
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 5 8
Fatty-acid amide hydrolase 1 inhibitor 3-[(3R)-1-[4-(1-benzofu... 4 4
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 6 1
Vascular endothelial growth factor receptor 1 and Receptor-typ... 2 11
Vascular endothelial growth factor receptor 1 ligand CHEMBL197... 1 2
Activated CDC42 kinase 1 inhibitor 6-(4-methylsulfonylphenyl)-... 2 0
Activated CDC42 kinase 1 inhibitor 6-[4-(2-morpholin-4-ylethox... 7 1
Eukaryotic translation initiation factor 2-alpha kinase 3 inhi... 2 0
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 6
Angiopoietin-1 receptor and Vascular endothelial growth factor... 5 0
Adenosine receptor A2a and Adenosine receptor A1 ligand 1-[(2-... 2 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 1
Adenosine kinase inhibitor AGN-PC-0757MS family 2 0
Receptor tyrosine-protein kinase erbB-2 ligand AGN-PC-03J2ZU f... 1 2
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 19 2
Neuropeptide Y receptor type 5 ligand SureCN2658856 family 6 0
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 9 0
Glycogen synthase kinase-3 beta inhibitor N-[4-(4-amino-6-pyri... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27744 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543