CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8614
Family Name Histamine H3 receptor ligand SureCN5093910 family
No. of Seeds 3 No. of Other Members 16
Family Centroid CFAMM00389204 Functional Category Bioactive
Superfamily Histamine H3 receptor and Sodium-dependent serotonin transporter Binder Superfamily 3
Class Class 280

Cousin Family NamesSeedsMembers
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Glycoprotein IIb/IIIa receptor Ligand Tirofiban Family 4 173
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Substance-P receptor Ligand Ezlopitant Family 10 207
Dapoxetine family 3 40
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
Histamine H3 receptor Ligand A-331440 Family 6 7
Histamine H3 receptor Ligand UCL-2138 Family 23 172
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 11
Neuropeptide Y receptor type 5 Ligand FR-230481 Family 2 17
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 41
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 2
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 13
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 10 15
Muscarinic acetylcholine receptor M2 ligand (2R)-4-cyclohexyl-... 12 0
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 11 2
Histamine H3 receptor ligand cyclohexyl-[4-(3-piperidin-1-ylpr... 4 1
Histamine H3 receptor and Sodium-dependent serotonin transport... 15 1
Carbonic anhydrase 14 and Carbonic anhydrase 9 inhibitor 1-(4-... 2 3
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 1 0
Carbonic anhydrase 7 and Carbonic anhydrase 14 inhibitor 4-(6-... 7 8
Histamine H3 receptor ligand SureCN6071181 family 2 1
Histamine H3 receptor ligand SureCN6109532 family 1 0
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 13 0
5-hydroxytryptamine receptor 7 ligand 4-fluoro-N-[1-[2-(2-phen... 6 3
Alpha-1A adrenergic receptor and D(2) dopamine receptor ligand... 5 20
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 7 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 1
Sodium-dependent serotonin transporter and Histamine H3 recept... 7 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 2 3
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 6
Estrogen receptor and Estrogen receptor beta ligand SureCN6716... 2 0
Neuropeptide Y receptor type 5 ligand N-[[4-[(2,3-dihydro-1,4-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00389206 CHEMBL1824251 Bioactive N-methyl-N-[4-[4-(3-piperidin-1-ylpropoxy)phenyl]cyclohexyl]benzenesulfonamide
CFAMM00389204 CHEMBL210410 Bioactive SureCN5093910
CFAMM00389195 CHEMBL378842 Bioactive SureCN5097441

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27046 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543