CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8616
Family Name Renin and Potassium voltage-gated channel subfamily H member 2 ligand (3S,4R)-N-[[2-chloro-5-(3-methoxypropyl)phenyl]methyl]-N-cyclopropyl-4-(3,4-difluorophenyl)-4-hydroxypiperidine-3-carboxamide family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00389221 Functional Category Bioactive
Superfamily Renin and Cytochrome P450 3A4 Binder Superfamily
Class Class 1649

Cousin Family NamesSeedsMembers
Delta-type opioid receptor Ligand Loperamide Family 8 55
Substance-K receptor ligand AGN-PC-0759BS family 3 6
Substance-P receptor and Substance-K receptor ligand N-[(2Z)-3... 5 0


External ID

Functional Category

Molecule Name

CFAMM00389221 CHEMBL1910296 Bioactive (3S,4R)-N-[[2-chloro-5-(3-methoxypropyl)phenyl]methyl]-N-cyclopropyl-4-(3,4-difluorophenyl)-4-hydroxypiperidine-3-carboxamide
CFAMM00389220 CHEMBL1910295 Bioactive (3S,4R)-N-cyclopropyl-N-[(2,3-dichlorophenyl)methyl]-4-(3,4-difluorophenyl)-4-hydroxypiperidine-3-carboxamide
CFAMM00389222 CHEMBL1824499 Bioactive (3S,4R)-N-[[2-chloro-5-(2-methoxyethyl)phenyl]methyl]-N-cyclopropyl-4-(3,4-difluorophenyl)-4-hydroxypiperidine-3-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



113593 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543