CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8618
Family Name Renin inhibitor [2-(5-fluoro-2-methylphenoxy)-5-hydroxy-1-phenylpyrrolo[2,3-b]pyridin-3-yl]-piperazin-1-ylmethanone family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00389256 Functional Category Bioactive
Superfamily Renin and Insulin-like growth factor 1 receptor Binder Superfamily
Class Class 1070

Cousin Family NamesSeedsMembers
Tyrosine kinase Inhibitor PKI166 Family 17 198
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 8 8
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 13 15
Hepatocyte growth factor receptor and Receptor-type tyrosine-p... 12 26
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Renin inhibitor AGN-PC-09M9MJ family 2 23
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 19
Renin inhibitor [2-(2,6-dimethylphenoxy)-6-methoxy-1-phenylpyr... 1 0
Renin inhibitor [2-(3-fluoro-2,6-dimethylphenoxy)-1-phenylpyrr... 5 12
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 7 3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 1 1
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4461871 f... 2 2
Angiopoietin-1 receptor and Vascular endothelial growth factor... 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00389256 CHEMBL1824626 Bioactive [2-(5-fluoro-2-methylphenoxy)-5-hydroxy-1-phenylpyrrolo[2,3-b]pyridin-3-yl]-piperazin-1-ylmethanone
CFAMM00389255 CHEMBL1824627 Bioactive [2-[(3-fluoro-2-methylphenyl)methyl]-5-hydroxy-1-phenylpyrrolo[2,3-b]pyridin-3-yl]-piperazin-1-ylmethanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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