CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8619
Family Name Renin inhibitor [2-(2,6-dimethylphenoxy)-6-methoxy-1-phenylpyrrolo[2,3-b]pyridin-3-yl]-piperazin-1-ylmethanone family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00389257 Functional Category Bioactive
Superfamily Renin and Insulin-like growth factor 1 receptor Binder Superfamily
Class Class 1070

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dibucaine F... 2 136
MK-6096 family 3 69
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Neuromedin-K receptor Ligand 3-methoxy-n',2-diphenylquinoline-... 14 33
Hepatocyte growth factor receptor and Receptor-type tyrosine-p... 12 26
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Renin inhibitor AGN-PC-09M9MJ family 2 23
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 3 3
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 3 21
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 19
Renin inhibitor [2-(5-fluoro-2-methylphenoxy)-5-hydroxy-1-phen... 2 0
Renin inhibitor [2-(3-fluoro-2,6-dimethylphenoxy)-1-phenylpyrr... 5 12
Cholinesterase and Acetylcholinesterase inhibitor 4-oxo-N-[9-(... 11 13
Rho-associated protein kinase 1 inhibitor SureCN4007647 family 8 4
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 8
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 6
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4461871 f... 2 2
Angiopoietin-1 receptor and Vascular endothelial growth factor... 5 0
RAF proto-oncogene serine/threonine-protein kinase inhibitor a... 8 6
Insulin-like growth factor 1 receptor ligand SureCN311483 family 3 0


External ID

Functional Category

Molecule Name

CFAMM00389257 CHEMBL1824630 Bioactive [2-(2,6-dimethylphenoxy)-6-methoxy-1-phenylpyrrolo[2,3-b]pyridin-3-yl]-piperazin-1-ylmethanone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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