CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8623
Family Name Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-3-(4'-hydroxy-2-oxospiro[1H-indole-3,1'-cyclohexane]-6-yl)-4-methylbenzamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00389281 Functional Category Bioactive
Superfamily Delta-type opioid receptor and Microsomal triglyceride transfer protein large subunit Binder Superfamily
Class Class 1365

Cousin Family NamesSeedsMembers
5-alpha reductase inhibitor azasteroid derivative Dutasteride ... 36 124
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
Mitogen-activated protein kinase 14 inhibitor 4-chloro-N-cyclo... 2 0
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 0
P2X purinoceptor 7 inhibitor 2-[3-fluoro-4-(trifluoromethyl)ph... 3 0
5-hydroxytryptamine receptor 7 ligand 3-ethyl-3-[4-[4-(4-fluor... 3 1
P2X purinoceptor 7 inhibitor 2-(1-adamantyl)-N-[2-(1-hydroxy-3... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00389281 CHEMBL1825151 Bioactive N-cyclopropyl-3-(4'-hydroxy-2-oxospiro[1H-indole-3,1'-cyclohexane]-6-yl)-4-methylbenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

44593 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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