CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8644
Family Name Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonyl-2-methylpyrrolidine-2-carbonyl]amino]-3-[4-(2,6-dimethoxyphenyl)phenyl]propanoic acid family
No. of Seeds 9 No. of Other Members 2
Family Centroid CFAMM00389465 Functional Category Bioactive
Superfamily Integrin beta-1 and Integrin alpha-4 Binder Superfamily 12
Class Class 2455

Cousin Family NamesSeedsMembers
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6368456 f... 3 23
Integrin beta-1 and Integrin alpha-4 inhibitor (3R)-3-[[(2S)-1... 12 0
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6367561 f... 20 12
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5686971 f... 19 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[4-(ben... 12 20
Integrin beta-1 and Integrin alpha-4 inhibitor AGN-PC-074GDW f... 9 2
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-ethy... 7 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(3-benz... 7 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[1-(ben... 6 5
Integrin beta-1 and Integrin alpha-4 inhibitor (4S)-4-[benzene... 7 0
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5686827 f... 7 3
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 2 0
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5687185 f... 7 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-1-(3,5-dic... 1 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 1 0
Integrin alpha-4 and Integrin beta-7 inhibitor (2S)-2-[[[(2S)-... 2 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00389465 CHEMBL56511 Bioactive (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonyl-2-methylpyrrolidine-2-carbonyl]amino]-3-[4-(2,6-dimethoxyphenyl)phenyl]propanoic acid
CFAMM00389464 CHEMBL1828839 Bioactive (2R)-3-[4-[2,6-bis(2-methylpropanoyloxy)phenyl]phenyl]-2-[[(2R)-1-(3,5-dichlorophenyl)sulfonyl-2-methylpyrrolidine-2-carbonyl]amino]propanoic acid
CFAMM00389470 CHEMBL278045 Bioactive (2S)-3-[4-[2,6-bis(2-methylpropanoyloxy)phenyl]phenyl]-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonyl-2-methylpyrrolidine-2-carbonyl]amino]propanoic acid
CFAMM00389469 CHEMBL292619 Bioactive (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonyl-2-methylpyrrolidine-2-carbonyl]amino]-3-[4-[2,6-dimethoxy-4-(pyrrolidin-1-ylmethyl)phenyl]phenyl]propanoic acid
CFAMM00389468 CHEMBL91737 Bioactive (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[4-(2,6-dimethoxyphenyl)phenyl]propanoic acid
CFAMM00389467 CHEMBL1829034 Bioactive (2R)-2-[[(2R)-1-(3,5-dichlorophenyl)sulfonyl-2-methylazetidine-2-carbonyl]amino]-3-[4-(2,6-dimethoxyphenyl)phenyl]propanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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