CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8656
Family Name Neuropeptide Y receptor type 5 ligand 2-(6-chloro-3,4-dihydro-2H-quinolin-1-yl)-N-[4-[(propan-2-ylsulfonylamino)methyl]cyclohexyl]acetamide family
No. of Seeds 5 No. of Other Members 1
Family Centroid CFAMM00389605 Functional Category Bioactive
Superfamily Neuropeptide Y receptor type 5 and Prothrombin Binder Superfamily
Class Class 435

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Melanocortin receptor 4 and Melanocortin receptor 5 ligand N-[... 16 117
Melanocortin receptor 4 and Melanocortin receptor 5 ligand AC1... 5 37
Melanocortin receptor 4 ligand (3R)-N-[(2R)-3-(4-chlorophenyl)... 6 9
Neuropeptide Y receptor type 5 ligand 2-(7-chloro-3-oxo-1,4-be... 4 1
Melanocortin receptor 4 ligand SureCN6183720 family 2 5
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 11 9
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 3 0
Melanocortin receptor 4 and Cytochrome P450 3A4 ligand 2-amino... 52 12
Melanocortin receptor 4 ligand N-[(1S)-1-[2-[4-[(3S,4R)-4-(4-c... 26 13
Substance-K receptor and Neuromedin-K receptor ligand 1-benzyl... 3 10
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand (3R,6... 5 3
Cannabinoid receptor 1 ligand N-[[(3R,6S)-1-(4-chlorophenyl)-6... 1 0


External ID

Functional Category

Molecule Name

CFAMM00389605 CHEMBL1829326 Bioactive 2-(6-chloro-3,4-dihydro-2H-quinolin-1-yl)-N-[4-[(propan-2-ylsulfonylamino)methyl]cyclohexyl]acetamide
CFAMM00389604 CHEMBL1829334 Bioactive N-[[4-[2-(6-chloro-3,4-dihydro-2H-quinolin-1-yl)ethylamino]cyclohexyl]methyl]propane-2-sulfonamide
CFAMM00389603 CHEMBL2013016 Bioactive 2-(5-chloro-3,3-dimethyl-2H-indol-1-yl)-N-[4-[(propan-2-ylsulfonylamino)methyl]cyclohexyl]acetamide
CFAMM00389606 CHEMBL1829325 Bioactive 2-(6-chloro-2-oxo-3,4-dihydroquinolin-1-yl)-N-[4-[(propan-2-ylsulfonylamino)methyl]cyclohexyl]acetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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