CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8659
Family Name Histamine H3 receptor ligand SureCN1373218 family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00389613 Functional Category Bioactive
Superfamily Histamine H3 receptor and Survival motor neuron protein Binder Superfamily 2
Class Class 3662

Cousin Family NamesSeedsMembers
Histamine H1 receptor and Histamine H3 receptor Ligand GSK1004... 13 18
Irdabisant family 49 53
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
Histamine H3 receptor Ligand A-349821 Family 49 228
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Liver carboxylesterase 1 Inhibitor SCH-48375 Family 2 28
Glycogen synthase kinase-3 beta inhibitor AGN-PC-07ZA1D family 6 9
Glycogen synthase kinase-3 beta inhibitor AGN-PC-07ZA5P family 4 11
Glycogen synthase kinase-3 beta inhibitor AGN-PC-07ZA3I family 6 1
Glycogen synthase kinase-3 beta inhibitor AGN-PC-07ZA03 family 4 0
Potassium voltage-gated channel subfamily H member 2 and Melan... 9 4
Histamine H1 receptor and Histamine H3 receptor ligand 4-[(4-m... 3 6
Histamine H3 receptor ligand 6-[3-chloro-4-[3-[(2R)-2-methylpy... 1 0
Histamine H3 receptor ligand 2-methyl-4-[4-(3-pyrrolidin-1-ylp... 4 1
Histamine H3 receptor ligand 3-methyl-1-[4-(3-piperidin-1-ylpr... 6 1
Histamine H3 receptor ligand 1-methyl-5-[4-[3-[(2R)-2-methylpy... 5 5
Histamine H3 receptor ligand 5-[4-[3-[(2R)-2-methylpyrrolidin-... 2 3
5-hydroxytryptamine receptor 3A ligand 5-[4-[3-(azepan-1-yl)pr... 2 0


External ID

Functional Category

Molecule Name

CFAMM00389613 CHEMBL1829470 Bioactive SureCN1373218

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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