CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8660
Family Name 5-hydroxytryptamine receptor 3A ligand 6-methyl-5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-pyridin-2-ylpyridazin-3-one family
No. of Seeds 12 No. of Other Members 3
Family Centroid CFAMM00389615 Functional Category Bioactive
Superfamily Beta-lactamase and Histamine H1 receptor Binder Superfamily 2
Class Class 1248

Cousin Family NamesSeedsMembers
Peroxisome proliferator-activated receptor gamma Ligand Piogli... 2 29
Histamine H1 receptor Ligand Mepyramine Family 5 65
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
Histamine H3 receptor ligand 6-[4-[3-[(2R)-2-methylpyrrolidin-... 1 0
Histamine H3 receptor ligand 3-[4-[3-[(2R)-2-methylpyrrolidin-... 1 5
Histamine H3 receptor ligand 6-[6-(1-cyclobutylpiperidin-4-yl)... 4 1
Histamine H3 receptor ligand [1-[(2-aminopyridin-4-yl)methyl]-... 2 2


External ID

Functional Category

Molecule Name

CFAMM00389617 CHEMBL1958331 Bioactive 2-(6-methylpyridin-2-yl)-5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
CFAMM00389623 CHEMBL1945849 Bioactive 5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-6-methyl-2-(6-methylpyridin-2-yl)pyridazin-3-one
CFAMM00389616 CHEMBL1958332 Bioactive 2-(3-methylpyridin-2-yl)-5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
CFAMM00389622 CHEMBL1829471 Bioactive 6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-pyridin-2-ylpyridazin-3-one
CFAMM00389615 CHEMBL1958333 Bioactive 6-methyl-5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-pyridin-2-ylpyridazin-3-one
CFAMM00389628 CHEMBL1945843 Bioactive 5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-pyridin-2-ylpyridazin-3-one
CFAMM00389620 CHEMBL1958334 Bioactive 6-methyl-2-(3-methylpyridin-2-yl)-5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
CFAMM00389626 CHEMBL1958329 Bioactive 5-[4-(3-piperidin-1-ylpropoxy)phenyl]-2-pyridin-2-ylpyridazin-3-one
CFAMM00389619 CHEMBL1950733 Bioactive 6-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-2-pyridin-2-ylpyridazin-3-one
CFAMM00389625 CHEMBL1945850 Bioactive 5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-6-methyl-2-(3-methylpyridin-2-yl)pyridazin-3-one
CFAMM00389618 CHEMBL1958330 Bioactive 5-[4-[3-(azepan-1-yl)propoxy]phenyl]-2-pyridin-2-ylpyridazin-3-one
CFAMM00389624 CHEMBL1945848 Bioactive 5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-6-methyl-2-pyridin-2-ylpyridazin-3-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



74035 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543