CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8662
Family Name Histamine H3 receptor ligand 3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-5-pyridin-2-yl-1H-pyridazin-6-one family
No. of Seeds 1 No. of Other Members 5
Family Centroid CFAMM00389637 Functional Category Bioactive
Superfamily Delta-type opioid receptor and Mu-type opioid receptor Ligand 6-(2-phenethylisoindolin-5-yloxy)nicotinamide Superfamily
Class Class 2449

Cousin Family NamesSeedsMembers
Peroxisome proliferator-activated receptor gamma Ligand Piogli... 2 29
Histamine H3 receptor Ligand GSK239512 Family 2 65
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
5-hydroxytryptamine receptor 1A Ligand Sun N4057 Family 2 86
Mu-type opioid receptor Ligand 6-(4-(2-(benzylamino)ethyl)phen... 3 27
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 57
Bifunctional epoxide hydrolase 2 Inhibitor N-benzyl-6-(3,3,3-t... 21 62
Neutrophil elastase inhibitor phenyl N-[(2S)-1-[(2S)-2-[[(3S)-... 2 0
Glycogen synthase kinase-3 beta inhibitor AGN-PC-07ZA5M family 4 14
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 5 1
Gonadotropin-releasing hormone receptor ligand 1-[(2,6-difluor... 6 31
Potassium voltage-gated channel subfamily H member 2 and Kappa... 5 33
Cytochrome P450 11B2, mitochondrial and Cytochrome P450 11B1, ... 9 7
5-hydroxytryptamine receptor 3A ligand 6-methyl-5-[4-[3-[(2R)-... 12 3
Histamine H3 receptor ligand 6-[4-[3-[(2R)-2-methylpyrrolidin-... 1 0
Mu-type opioid receptor ligand AGN-PC-075GBK family 4 4
Histamine H3 receptor ligand 6-[6-(1-cyclobutylpiperidin-4-yl)... 4 1
Histamine H3 receptor ligand 2-[4-(1-methylpyrrole-2-carbonyl)... 3 4
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cGMP-inhib... 18 10
Glutamate receptor ionotropic, NMDA 2B ligand SureCN5532501 fa... 1 0
72 kDa type IV collagenase and Aminopeptidase N inhibitor ly52... 1 0
Acyl-CoA desaturase inhibitor SureCN1182719 family 1 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 3 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00389637 CHEMBL1829474 Bioactive 3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-5-pyridin-2-yl-1H-pyridazin-6-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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