CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8664
Family Name Cathepsin K and Cathepsin S inhibitor (2S)-N-(cyanomethyl)-4-methyl-2-[[4-(4-piperazin-1-ylphenyl)thiophen-3-yl]amino]pentanamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00389638 Functional Category Bioactive
Superfamily Cathepsin K and Cathepsin S Binder Superfamily 10
Class Class 1000

Cousin Family NamesSeedsMembers
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 12 16
Histone deacetylase 1 and Potassium voltage-gated channel subf... 4 36
Prelamin-A/C inhibitor CHEMBL1547148 family 1 8
Vasopressin V2 receptor and Vasopressin V1a receptor ligand 2-... 6 9
D(4) dopamine receptor ligand 1-Piperidineacetamide, 4-(2-cyan... 3 7
Calcitonin gene-related peptide type 1 receptor and Cytochrome... 4 7
Coagulation factor X and Prothrombin inhibitor SureCN14502287 ... 16 5
Transient receptor potential M8 protein ligand 2-(1-benzothiop... 1 0
Histone deacetylase 1 inhibitor SureCN3642893 family 10 23
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 10 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 7 5
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 3
5-hydroxytryptamine receptor 1A ligand (3R)-N-(1-adamantyl)-1,... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00389638 CHEMBL182956 Bioactive (2S)-N-(cyanomethyl)-4-methyl-2-[[4-(4-piperazin-1-ylphenyl)thiophen-3-yl]amino]pentanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42566 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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