CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8671
Family Name Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 3-[3-(2,4-difluorophenyl)phenyl]-6-methyl-6-phenyl-1,3-oxazinan-2-one family
No. of Seeds 7 No. of Other Members 18
Family Centroid CFAMM00389672 Functional Category Bioactive
Superfamily Sodium-dependent dopamine transporter and Substance-P receptor Binder Superfamily
Class Class 1826

Cousin Family NamesSeedsMembers
Progesterone receptor ligand SureCN3874009 family 2 7
Cathepsin L1 and Cathepsin K inhibitor benzyl N-[(2S)-4-methyl... 8 22
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Cytochrome ... 11 4
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Cytochrome ... 12 2
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 1 8
Progesterone receptor ligand SureCN4841866 family 2 10
Progesterone receptor ligand SureCN4841913 family 3 7
Sodium-dependent dopamine transporter and Sigma non-opioid int... 5 8
Melanin-concentrating hormone receptor 1 and Alpha-1A adrenerg... 1 0
D(4) dopamine receptor and 5-hydroxytryptamine receptor 2C lig... 1 7
Mu-type opioid receptor and Nociceptin receptor ligand AGN-PC-... 2 7
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 3


External ID

Functional Category

Molecule Name

CFAMM00389674 CHEMBL1829752 Bioactive 3-[3-(3-fluorophenyl)phenyl]-6-methyl-6-phenyl-1,3-oxazinan-2-one
CFAMM00389673 CHEMBL1829755 Bioactive 3-[3-(2,4-difluorophenyl)phenyl]-6-phenyl-6-prop-2-enyl-1,3-oxazinan-2-one
CFAMM00389672 CHEMBL1829754 Bioactive 3-[3-(2,4-difluorophenyl)phenyl]-6-methyl-6-phenyl-1,3-oxazinan-2-one
CFAMM00389671 CHEMBL1829757 Bioactive 3-[3-(2,4-difluorophenyl)phenyl]-6-(3-hydroxypropyl)-6-phenyl-1,3-oxazinan-2-one
CFAMM00389670 CHEMBL1829756 Bioactive 3-[3-(2,4-difluorophenyl)phenyl]-6-(2-hydroxyethyl)-6-phenyl-1,3-oxazinan-2-one
CFAMM00389676 CHEMBL1829750 Bioactive 6-methyl-6-phenyl-3-(3-phenylphenyl)-1,3-oxazinan-2-one
CFAMM00389675 CHEMBL1829753 Bioactive 3-[3-(4-fluorophenyl)phenyl]-6-methyl-6-phenyl-1,3-oxazinan-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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