CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8678
Family Name Melanin-concentrating hormone receptor 1 ligand 4-(4-chlorophenyl)-1-[1-(1-methylazetidin-3-yl)-2,3-dihydroindol-5-yl]pyridin-2-one family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00389745 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 2A Ligand 1-methyl-1,3-dihydro-indol-2-one Superfamily
Class Class 3044

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 23
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 0
D(4) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 1 0
Melanocortin receptor 4 and Melanocortin receptor 5 ligand N-[... 16 117
C-C chemokine receptor type 1 ligand SureCN3159355 family 7 9
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 11 9
P2X purinoceptor 7 inhibitor SureCN3726471 family 3 0
P2X purinoceptor 7 inhibitor AGN-PC-088GOO family 3 0
P2X purinoceptor 7 inhibitor SureCN3721807 family 3 0
Melanocortin receptor 4 and Cytochrome P450 3A4 ligand 2-amino... 52 12
Melanocortin receptor 4 ligand N-[(1S)-1-[2-[4-[(3S,4R)-4-(4-c... 26 13
Urotensin-2 receptor and Cytochrome P450 2D6 ligand 2-[3,4-dic... 2 3
Kappa-type opioid receptor and Urotensin-2 receptor ligand 2-(... 5 1
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 4 1
Progesterone receptor ligand CHEMBL403139 family 2 0
Potassium voltage-gated channel subfamily H member 2 and D(3) ... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00389745 CHEMBL1830052 Bioactive 4-(4-chlorophenyl)-1-[1-(1-methylazetidin-3-yl)-2,3-dihydroindol-5-yl]pyridin-2-one
CFAMM00389744 CHEMBL1830053 Bioactive 4-(4-chlorophenyl)-1-[1-[1-(2-fluoroethyl)azetidin-3-yl]-2,3-dihydroindol-5-yl]pyridin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27759 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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