CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8681
Family Name Corticotropin-releasing factor receptor 1 ligand CHEMBL1830528 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00389768 Functional Category Bioactive
Superfamily Corticotropin-releasing factor receptor 1 Ligand BMS-561388 Superfamily
Class Class 2074

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Trimethoprim Family 67 482
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
Hypoxia-inducible factor 1-alpha Inhibitor Hif-1alpha Family 7 107
Insulin-like growth factor 1 receptor Ligand AEW-541 Family 12 140
Corticotropin-releasing factor receptor 1 Ligand GSK561679 Family 5 6
Corticotropin-releasing factor receptor 1 Ligand GW876008 Family 3 30
Hepatocyte growth factor receptor Ligand Amg 208 Family 20 236
Ibrutinib family 2 27
Peptide deformylase, mitochondrial Inhibitor Epiroprim Family 5 68
Vascular endothelial growth factor receptor 2 Ligand L00002164... 6 23
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 37
Corticotropin-releasing factor receptor 1 Ligand BMS-561388 Fa... 10 16
Serine/threonine-protein kinase B-raf inhibitor SureCN1015955 ... 17 18
Adenosine receptor A3 and Adenosine receptor A2a ligand AGN-PC... 3 4
Serine/threonine-protein kinase B-raf inhibitor 3-[7-[4-[[(3R)... 6 7
Adenosine receptor A3 ligand AGN-PC-07N4XZ family 4 11
Adenosine receptor A3 ligand CHEMBL1834696 family 5 18
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 31 11
Proto-oncogene tyrosine-protein kinase Src and Phosphatidylino... 4 20
Tyrosine-protein kinase ABL1 and Tyrosine-protein kinase HCK i... 2 2
Proto-oncogene tyrosine-protein kinase Src and Tyrosine-protei... 12 8
Cellular tumor antigen p53 inhibitor CHEMBL1401545 family 1 25
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN7... 3 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 4
Lethal factor and Dual specificity protein kinase CLK4 inhibit... 1 3
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 6
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 5 1
Calmodulin-domain protein kinase 1 and Tyrosine-protein kinase... 5 5
Corticotropin-releasing factor receptor 1 ligand CHEMBL1819076... 2 0
TGF-beta receptor type-1 ligand N-(4-methoxyphenyl)-3-(6-methy... 5 2
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 4 9
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 2
Adenosine kinase inhibitor (2R,3R,4R)-2-[4-(2,3-dihydro-1,4-be... 5 2
Macrophage colony-stimulating factor 1 receptor and Ephrin typ... 1 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 25 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
Estrogen receptor and Estrogen receptor beta ligand 4-[3-[4-(2... 1 0
Metabotropic glutamate receptor 2 ligand 8-chloro-3-(cycloprop... 6 2
Adenosine receptor A2a and Cytochrome P450 3A4 ligand N-[6-(3,... 5 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 1 0
cGMP-dependent 3',5'-cyclic phosphodiesterase inhibitor SureCN... 4 0
Tyrosine-protein kinase JAK2 inhibitor (2R)-2-[4-[[8-(4-methox... 2 0
Hepatocyte growth factor receptor ligand 6-[(1S)-1-[6-(2,3-dih... 1 5
Adenosine receptor A2a ligand 8-(3-fluorophenyl)-3-[2-[4-[4-(2... 5 0
Cathepsin K and Cathepsin S inhibitor SureCN4135077 family 2 0
Tyrosine-protein kinase Lck and Vascular endothelial growth fa... 1 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 5 0
Activated CDC42 kinase 1 and Tyrosine-protein kinase Lck inhib... 4 0
Oxytocin receptor and Vasopressin V1a receptor ligand AGN-PC-0... 4 3
Corticotropin-releasing factor receptor 1 ligand AGN-PC-068CCL... 3 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
Acyl-CoA desaturase 1 inhibitor Pyridazine, 3-[4-(2-ethylpheno... 4 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D inhibitor Sure... 2 6
Tyrosine-protein kinase Lck and Vascular endothelial growth fa... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00389768 CHEMBL1830528 Bioactive CHEMBL1830528

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26224 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543