CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8701
Family Name Thyroid hormone receptor alpha and Thyroid hormone receptor beta ligand AGN-PC-00DYD6 family
No. of Seeds 2 No. of Other Members 11
Family Centroid CFAMM00389911 Functional Category Bioactive with Natural Product
Superfamily Substance-P receptor and Leukotriene B4 receptor 1 Binder Superfamily
Class Class 2449

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand monosubstituted indole derivat... 14 475
Melatonin receptor type 1A Ligand Melatonin Family 20 988
DNA Binder Elliptinium Acetate Family 11 116
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 11 49
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 12 197
Apricoxib family 8 77
Indeglitazar family 3 39
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 11 41
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 13 22
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Oestrogen receptor and Estrogen receptor beta Ligand Pipendoxi... 11 48
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 2 0
Alpha-1A adrenergic receptor Ligand RS-17053 Family 9 6
Vascular endothelial growth factor receptor 1 Ligand Lycogarub... 6 292
D(2) dopamine receptor Ligand SLV-314 Family 19 69
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 4 32
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Cannabinoid receptor 1 Ligand 1-(2-morpholinoethyl)-1h-indol-3... 8 46
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 16
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 17 69
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 6
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 48
Vascular endothelial growth factor receptor 2 ligand indolyl q... 2 1
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 8 21
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 5
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 2 5
Prelamin-A/C inhibitor 1-[(3,4-dimethoxyphenethyl)amino]-3-(1H... 1 2
Somatostatin receptor type 2 ligand tert-butyl (2S)-6-amino-2-... 2 15
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 3 3
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-3-... 8 3
Glucagon receptor and Mitogen-activated protein kinase 14 liga... 6 5
Integrin alpha-V and Integrin beta-5 inhibitor SureCN2491273 f... 11 10
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 1
Retinoic acid receptor RXR-alpha ligand (E)-3-[3-(3,5-ditert-b... 5 5
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 16 19
Sodium-dependent serotonin transporter inhibitor SureCN7536104... 6 2
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 3 0
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 2 3
RAC-alpha serine/threonine-protein kinase inhibitor 5-[5-[(2S)... 14 2
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 42 20
Peroxisome proliferator-activated receptor delta and Peroxisom... 1 1
5-hydroxytryptamine receptor 6 ligand 2-methyl-5-(2-nitropheno... 1 6
Estrogen receptor and Estrogen receptor beta ligand N-[(2R)-4-... 7 11
D(2) dopamine receptor and D(4) dopamine receptor ligand AGN-P... 1 0
Substance-P receptor ligand N-[(2R)-1-[acetyl-[(2-chlorophenyl... 2 2
Substance-P receptor ligand SureCN2139814 family 7 7
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 9
Substance-P receptor ligand AGN-PC-00FIT5 family 3 11
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
Protein kinase C theta type and Protein kinase C delta type in... 10 7
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 18 0
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 5 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 0
Acetylcholinesterase and Cholinesterase inhibitor P10358 family 2 0
Caspase-3 and Caspase-7 inhibitor (2S)-N-[(3S)-2-hydroxy-5-oxo... 4 1
ATP-binding cassette sub-family G member 2 inhibitor 5-[(4-bro... 1 1
Peroxisome proliferator-activated receptor gamma and Peroxisom... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00389911 CHEMBL183176 Bioactive AGN-PC-00DYD6
CFAMM00389917 CHEMBL360137 Bioactive AGN-PC-075DIZ

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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