CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8727
Family Name Histone deacetylase 1 inhibitor N-hydroxy-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)amino]pyrimidine-5-carboxamide family
No. of Seeds 7 No. of Other Members 4
Family Centroid CFAMM00390049 Functional Category Bioactive
Superfamily Histone deacetylase 1 and Retinal dehydrogenase 1 Binder Superfamily
Class Class 1070

Cousin Family NamesSeedsMembers
Adenosine receptor A3 ligand AGN-PC-07N4XZ family 4 11
Vascular endothelial growth factor receptor 2 and Vascular end... 1 9
Vascular endothelial growth factor receptor 2 and Vascular end... 8 1


External ID

Functional Category

Molecule Name

CFAMM00390052 CHEMBL1834466 Bioactive 2-[[5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl]amino]-N-hydroxypyrimidine-5-carboxamide
CFAMM00390051 CHEMBL1834461 Bioactive 2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]amino]-N-hydroxypyrimidine-5-carboxamide
CFAMM00390050 CHEMBL1834463 Bioactive N-hydroxy-2-[[5-(4-nitrophenyl)-1,3,4-oxadiazol-2-yl]amino]pyrimidine-5-carboxamide
CFAMM00390049 CHEMBL1834462 Bioactive N-hydroxy-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)amino]pyrimidine-5-carboxamide
CFAMM00390056 CHEMBL1834471 Bioactive 2-[[5-[4-(dimethylamino)phenyl]-1,3,4-oxadiazol-2-yl]amino]-N-hydroxypyrimidine-5-carboxamide
CFAMM00390046 CHEMBL1834469 Bioactive 2-[[5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl]amino]-N-hydroxypyrimidine-5-carboxamide
CFAMM00390045 CHEMBL1834468 Bioactive 2-[[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl]amino]-N-hydroxypyrimidine-5-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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