CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8735
Family Name B1 bradykinin receptor ligand 4-(4-methyl-1-oxophthalazin-2-yl)-N-[(1S)-6-(piperidin-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-yl]benzamide family
No. of Seeds 5 No. of Other Members 27
Family Centroid CFAMM00390147 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 2A and Ferritin light chain Binder Superfamily
Class Class 1365

Cousin Family NamesSeedsMembers
Poly [ADP-ribose] polymerase 1 Inhibitor KU-0059436 Family 21 45
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Poly [ADP-ribose] polymerase 1 Inhibitor KU-58684 Family 6 40
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Rho-associated protein kinase 2 inhibitor N-(7-chloro-1-oxo-2H... 13 42
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 9 8
Adenosine receptor A3 ligand AGN-PC-09M0WF family 1 1
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 3
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 8 1
Melanin-concentrating hormone receptor 1 ligand N-[3-[1-[3-[4-... 4 13
Poly [ADP-ribose] polymerase 1 inhibitor 8-[[4-fluoro-3-(4-phe... 2 0
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 5
Acetylcholinesterase and Butyrylcholinesterase inhibitor 4-N-m... 3 11


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00390129 CHEMBL1834618 Bioactive 4-(6-chloro-4-methyl-1-oxophthalazin-2-yl)-N-[(1R)-6-(piperidin-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-yl]benzamide
CFAMM00390135 CHEMBL1834616 Bioactive 4-(8-chloro-4-methyl-1-oxophthalazin-2-yl)-N-[(1R)-6-(piperidin-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-yl]benzamide
CFAMM00390147 CHEMBL1934253 Bioactive 4-(4-methyl-1-oxophthalazin-2-yl)-N-[(1S)-6-(piperidin-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-yl]benzamide
CFAMM00390146 CHEMBL1834614 Bioactive 4-(8-fluoro-4-methyl-1-oxophthalazin-2-yl)-N-[(1R)-6-(piperidin-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-yl]benzamide
CFAMM00390145 CHEMBL1834615 Bioactive 4-(5,8-difluoro-4-methyl-1-oxophthalazin-2-yl)-N-[(1R)-6-(piperidin-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-yl]benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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