CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8754
Family Name Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 inhibitor 1-[[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]amino]-7-[6-(1,1-dioxo-1,4-thiazinan-4-yl)pyridazin-3-yl]-5H-pyrido[4,3-b]indole-4-carboxamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00389950 Functional Category Bioactive
Superfamily XL-888 Superfamily
Class Class 1053

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase B-raf Inhibitor Pyrazolo[1,5-a... 7 77
Sphingosine 1-phosphate receptor 1 ligand SureCN3029336 family 4 8
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 10
Mitogen-activated protein kinase 14 inhibitor AGN-PC-09M6OU fa... 8 7
Mitogen-activated protein kinase 14 inhibitor AGN-PC-069K8I fa... 12 3
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 13 3
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 2
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 2 3
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 2 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 10 0
DNA gyrase subunit B inhibitor 5-[2-(ethylcarbamoyl)-4-[3-(tri... 2 4
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-fluoro... 5 1
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 12 3
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27257 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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