CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8758
Family Name Neuronal acetylcholine receptor subunit alpha-4 and Neuronal acetylcholine receptor subunit beta-2 ligand 5-[5-[[(2S)-azetidin-2-yl]methoxy]pyridin-3-yl]-3-ethyl-1,2-oxazole family
No. of Seeds 15 No. of Other Members 4
Family Centroid CFAMM00373555 Functional Category Bioactive
Superfamily Neuronal acetylcholine receptor subunit beta-2 and Neuronal acetylcholine receptor subunit alpha-4 Binder Superfamily 4
Class Class 2009

Cousin Family NamesSeedsMembers
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 7


External ID

Functional Category

Molecule Name

CFAMM00390316 CHEMBL2178872 Bioactive 5-[5-[[(2S)-azetidin-2-yl]methoxy]pyridin-3-yl]-3-(3,3,3-trifluoropropyl)-1,2-oxazole
CFAMM00390315 CHEMBL1852406 Bioactive 2-[5-[5-[[(2S)-azetidin-2-yl]methoxy]pyridin-3-yl]-1,2-oxazol-3-yl]ethanol
CFAMM00390308 CHEMBL2178329 Bioactive 3-[5-[5-[[(2S)-pyrrolidin-2-yl]methoxy]pyridin-3-yl]-1,2-oxazol-3-yl]propan-1-ol
CFAMM00390314 CHEMBL1835609 Bioactive 3-[5-[5-[[(2S)-azetidin-2-yl]methoxy]pyridin-3-yl]-1,2-oxazol-3-yl]propan-1-ol;hydrochloride
CFAMM00390306 CHEMBL2178333 Bioactive 5-[5-[[(2S)-azetidin-2-yl]methoxy]pyridin-3-yl]-3-(3-fluoropropyl)-1,2-oxazole
CFAMM00390312 CHEMBL1835611 Bioactive 2-[5-[5-[[(2S)-azetidin-2-yl]methoxy]pyridin-3-yl]-1,2-oxazol-3-yl]ethanol;hydrochloride
CFAMM00390305 CHEMBL2178332 Bioactive 5-[5-[[(2S)-azetidin-2-yl]methoxy]pyridin-3-yl]-3-(3,3-difluoropropyl)-1,2-oxazole
CFAMM00390311 CHEMBL1835610 Bioactive [5-[5-[[(2S)-azetidin-2-yl]methoxy]pyridin-3-yl]-1,2-oxazol-3-yl]methanol;hydrochloride

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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