CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8760
Family Name Histamine H3 receptor ligand 2-methyl-4-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]phthalazin-1-one family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00390327 Functional Category Bioactive
Superfamily Histamine H1 receptor and Histamine H3 receptor Ligand GSK1004723 Superfamily
Class Class 989

Cousin Family NamesSeedsMembers
Histamine H1 receptor and Histamine H3 receptor Ligand GSK1004... 13 18
Irdabisant family 49 53
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 3 89
Histamine H3 receptor Ligand A-349821 Family 49 228
Urotensin-2 receptor Ligand SB-328872 Family 5 24
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 2
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 2
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 3 10
Survival motor neuron protein inhibitor CHEMBL1303282 family 1 1
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 7 4
Histamine H1 receptor and Histamine H3 receptor ligand 4-[(4-m... 3 6
Histamine H3 receptor ligand SureCN1373218 family 2 2
Histamine H3 receptor ligand 6-[3-chloro-4-[3-[(2R)-2-methylpy... 1 0
Histamine H3 receptor ligand 7-[4-[3-[(2R)-2-methylpyrrolidin-... 5 1
Histamine H3 receptor ligand 3-methyl-1-[4-(3-piperidin-1-ylpr... 6 1
Histamine H3 receptor ligand 1-methyl-5-[4-[3-[(2R)-2-methylpy... 5 5
Histamine H3 receptor ligand (4R)-3-[4-(1-cyclobutylpiperidin-... 4 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 7 13
5-hydroxytryptamine receptor 3A ligand 5-[4-[3-(azepan-1-yl)pr... 2 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 8 4
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 3 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and Sodium-dep... 2 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4D inhibitor (4aS... 10 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00390327 CHEMBL1835707 Bioactive 2-methyl-4-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]phthalazin-1-one
CFAMM00390326 CHEMBL1835706 Bioactive 2-methyl-4-[4-(3-piperidin-1-ylpropoxy)phenyl]phthalazin-1-one
CFAMM00390325 CHEMBL1835704 Bioactive 2-methyl-4-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]phthalazin-1-one
CFAMM00390324 CHEMBL1835708 Bioactive 4-[4-[3-(azepan-1-yl)propoxy]phenyl]-2-methylphthalazin-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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