CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8764
Family Name Histamine H3 receptor ligand 7-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-5-propan-2-ylthieno[2,3-d]pyridazin-4-one family
No. of Seeds 5 No. of Other Members 1
Family Centroid CFAMM00390344 Functional Category Bioactive
Superfamily Beta-lactamase and Histamine H3 receptor Binder Superfamily 5
Class Class 4506

Cousin Family NamesSeedsMembers
Histamine H1 receptor and Histamine H3 receptor Ligand GSK1004... 13 18
Urotensin-2 receptor Ligand SB-328872 Family 5 24
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 3 10
Histamine H3 receptor ligand 2-methyl-4-[4-(3-pyrrolidin-1-ylp... 4 1
Histamine H3 receptor ligand SureCN5093846 family 2 3
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 2 4
Vesicular acetylcholine transporter and Sigma non-opioid intra... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00390344 CHEMBL1835772 Bioactive 7-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-5-propan-2-ylthieno[2,3-d]pyridazin-4-one
CFAMM00390343 CHEMBL1835777 Bioactive 5-propan-2-yl-7-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]thieno[2,3-d]pyridazin-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27072 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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