CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8765
Family Name Histamine H3 receptor ligand 3-methyl-1-[4-(3-piperidin-1-ylpropoxy)phenyl]-5,6,7,7a-tetrahydro-4aH-cyclopenta[d]pyridazin-4-one family
No. of Seeds 6 No. of Other Members 1
Family Centroid CFAMM00390347 Functional Category Bioactive
Superfamily Histamine H3 receptor Binder Superfamily 6
Class Class 3665

Cousin Family NamesSeedsMembers
Histamine H1 receptor and Histamine H3 receptor Ligand GSK1004... 13 18
Irdabisant family 49 53
Histamine H3 receptor Ligand A-349821 Family 49 228
Survival motor neuron protein inhibitor CHEMBL1303282 family 1 1
Histamine H1 receptor and Histamine H3 receptor ligand 4-[(4-m... 3 6
Histone deacetylase 2 and Histone deacetylase 3 inhibitor N'-h... 1 2
Histamine H3 receptor ligand SureCN1373218 family 2 2
Histamine H3 receptor ligand 6-[3-chloro-4-[3-[(2R)-2-methylpy... 1 0
Histamine H3 receptor ligand 2-methyl-4-[4-(3-pyrrolidin-1-ylp... 4 1
Histamine H3 receptor ligand 1-methyl-5-[4-[3-[(2R)-2-methylpy... 5 5
Histamine H3 receptor ligand (4R)-3-[4-(1-cyclobutylpiperidin-... 4 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 7 13
5-hydroxytryptamine receptor 3A ligand 5-[4-[3-(azepan-1-yl)pr... 2 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 8 4
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 5 14
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 3 6
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 3 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 1 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and Sodium-dep... 2 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4D inhibitor (4aS... 10 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00390348 CHEMBL1835787 Bioactive 2-methyl-4-[4-(3-piperidin-1-ylpropoxy)phenyl]-5,6,7,8-tetrahydrophthalazin-1-one
CFAMM00390347 CHEMBL1835785 Bioactive 3-methyl-1-[4-(3-piperidin-1-ylpropoxy)phenyl]-5,6,7,7a-tetrahydro-4aH-cyclopenta[d]pyridazin-4-one
CFAMM00390346 CHEMBL1835784 Bioactive 3-methyl-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-5,6,7,7a-tetrahydro-4aH-cyclopenta[d]pyridazin-4-one
CFAMM00390345 CHEMBL1835783 Bioactive 3-methyl-1-[4-(3-piperidin-1-ylpropoxy)phenyl]-6,7-dihydro-5H-cyclopenta[d]pyridazin-4-one
CFAMM00390349 CHEMBL1935105 Bioactive 6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-(2,2,2-trifluoroethyl)-4,5-dihydropyridazin-3-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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