CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8766
Family Name Casein kinase II subunit alpha inhibitor AGN-PC-0766PM family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00390354 Functional Category Bioactive
Superfamily Omega 1 Benzodiazepine receptor Ligand Zaleplon Superfamily
Class Class 195

Cousin Family NamesSeedsMembers
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
Tyrosine-protein kinase Lck and Aurora kinase B Inhibitor VX-6... 28 56
HER Inhibitor AC480 Family 4 67
Tyrosine-protein kinase JAK2 Inhibitor INCB18424 Family 3 130
C-reactive protein Inhibitor ISIS-CRP Family 4 105
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor PF-0048... 2 13
PF-4217903 family 14 65
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Adenosine receptor A2a and Adenosine receptor A3 Ligand 5-buty... 3 18
Glycogen synthase kinase-3 beta Inhibitor N-(6-(pyridin-4-yl)-... 4 23
Mitogen-activated protein kinase 3 and RAF proto-oncogene seri... 8 5
Cyclin-dependent kinase 2 and Mitogen-activated protein kinase... 7 30
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-phen... 8 11
Aurora kinase B and Tyrosine-protein kinase Lck Inhibitor CGP-... 2 29
Xanthine dehydrogenase/oxidase Inhibitor 3,5-di(pyridin-4-yl)-... 6 3
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
Serine/threonine-protein kinase B-raf Inhibitor Pyrazolo[1,5-a... 7 77
Adenosine receptor A3 and Adenosine receptor A2a ligand 5-buty... 3 13
Prothrombin inhibitor SureCN5854779 family 4 9
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... 8 7
Adenosine receptor A3 and Adenosine receptor A2a ligand AGN-PC... 3 18
Adenosine receptor A3 and Adenosine receptor A1 ligand AGN-PC-... 5 1
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 2 5
cGMP-specific 3',5'-cyclic phosphodiesterase and Potassium vol... 13 4
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 34 11
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN5... 6 24
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 46 9
Ephrin type-B receptor 4 ligand SureCN3289519 family 4 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 13 10
Platelet-activating factor receptor ligand SureCN9384429 family 11 3
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 6 1
Serine/threonine-protein kinase D1 and Polycystin-2 inhibitor ... 3 7
Aurora kinase A and Aurora kinase B inhibitor 3uol family 6 5
Adenosine receptor A3 and Adenosine receptor A2a ligand SureCN... 8 7
DNA-dependent protein kinase catalytic subunit and Tyrosine-pr... 2 10
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 3 11
Serine/threonine-protein kinase B-raf inhibitor SureCN3495787 ... 8 1
Mitogen-activated protein kinase 14 inhibitor AGN-PC-09M6OU fa... 8 7
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-(4-a... 8 11
Adenosine receptor A2a ligand AGN-PC-077RWY family 4 5
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 7 9
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 8
Prothrombin and Survival motor neuron protein inhibitor CHEMBL... 2 14
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Nuclear receptor ROR-gamma and 15-hydroxyprostaglandin dehydro... 1 1
Survival motor neuron protein inhibitor CHEMBL1583999 family 1 3
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 3 7
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 1 1
Cyclin-dependent kinase 2 and Glycogen synthase kinase-3 beta ... 2 3
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Aurora kinase A and Cyclin-dependent kinase 1 inhibitor N-[4-[... 12 2
Adenosine receptor A3 and Adenosine receptor A1 ligand CHEMBL1... 7 4
TGF-beta receptor type-1 ligand 3-(6-methylpyridin-2-yl)-N-phe... 21 0
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 1
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 0
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 1
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 3
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206623 family 10 11
Tyrosine-protein kinase JAK2 and Focal adhesion kinase 1 inhib... 11 3
Mast/stem cell growth factor receptor Kit and Receptor-type ty... 8 3
Vascular endothelial growth factor receptor 1 and Vascular end... 4 0
Protein kinase C theta type and Leucine-rich repeat serine/thr... 1 1
Tyrosine-protein kinase Mer and Tyrosine-protein kinase recept... 5 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 7 15
Casein kinase II subunit alpha and Homeodomain-interacting pro... 5 0
Casein kinase II subunit alpha inhibitor N-[5-[[3-cyano-7-(cyc... 3 0
Casein kinase II subunit alpha inhibitor 7-(cyclopropylamino)-... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 2
Cyclin-dependent kinase 2 and MAP kinase-activated protein kin... 3 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 6 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 3 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 1
Tyrosine-protein kinase JAK2 inhibitor N-[3-(3-chlorophenyl)-1... 12 4
Tyrosine-protein kinase SYK and Potassium voltage-gated channe... 1 0
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 17 0
Adenosine receptor A1 and Adenosine receptor A2a ligand AGN-PC... 4 2
Serine/threonine-protein kinase TBK1 inhibitor N-[3-[[5-cyclop... 3 0
Casein kinase II subunit alpha inhibitor 2pvj family 3 1
Tyrosine-protein kinase ABL1 and Abelson tyrosine-protein kina... 3 0
Fatty-acid amide hydrolase 1 inhibitor 4-(3-phenyl-1,2,4-thiad... 2 1
Motilin receptor ligand SureCN2004322 family 2 1
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 6 0
Mast/stem cell growth factor receptor Kit and Proto-oncogene t... 3 5
Proto-oncogene tyrosine-protein kinase Src and Mast/stem cell ... 4 1
Casein kinase II subunit alpha inhibitor N-[2-chloro-5-[[3-cya... 2 0
Casein kinase II subunit alpha inhibitor N-[5-[[3-cyano-7-(cyc... 9 0
Casein kinase II subunit alpha inhibitor N-[5-[[3-cyano-7-[(1-... 9 0
Tyrosine-protein kinase JAK2 inhibitor N-(3-methylphenyl)-5-(3... 2 4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 1
Cathepsin K and Cathepsin S inhibitor SureCN4138353 family 3 0
Casein kinase II subunit alpha inhibitor CHEMBL401945 family 12 1
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 6 6
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 4 7
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 13
Activated CDC42 kinase 1 inhibitor AGN-PC-078WDN family 7 2
Cyclin-dependent kinase 2 inhibitor SureCN3549598 family 3 1
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 11 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 26 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00390352 CHEMBL230354 Bioactive N-(3-(8-cyano-4-(phenylamino)pyrazolo[1,5-a][1,3,5]triazin-2-ylamino)phenyl)acetamide
CFAMM00390355 CHEMBL398149 Bioactive AGN-PC-0766PL
CFAMM00390354 CHEMBL230462 Bioactive AGN-PC-0766PM

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

46003 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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