CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM877
Family Name Endothelin-1 receptor and Endothelin B receptor ligand SureCN14203762 family
No. of Seeds 3 No. of Other Members 16
Family Centroid CFAMM00316755 Functional Category Bioactive
Superfamily Endothelin-1 receptor and Endothelin B receptor Binder Superfamily 2
Class Class 3074

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor 5-hexy... 4 5
Endothelin-1 receptor and Endothelin B receptor ligand (5S,6R,... 15 28
Endothelin-1 receptor and Endothelin B receptor ligand (5S,6R,... 23 8
Endothelin-1 receptor and Endothelin B receptor ligand 3-(1,3-... 1 1
Leukotriene B4 receptor 1 ligand AGN-PC-04XM3V family 3 10
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(1,3-ben... 6 5
Leukotriene B4 receptor 1 ligand SureCN8987047 family 4 3
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 7 4
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(1,3-ben... 8 3
Nitric oxide synthase, inducible inhibitor SureCN5194847 family 24 48
Nitric oxide synthase, inducible inhibitor N-(1,3-benzodioxol-... 11 1
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 3 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00316741 CHEMBL322537 Bioactive (2S,3R,4S)-4-(1,3-benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(2-pyrazol-1-ylethyl)pyrrolidine-3-carboxylic acid
CFAMM00316756 CHEMBL109778 Bioactive (2S,3R,4S)-4-(1,3-benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(2-pyridin-2-ylethyl)pyrrolidine-3-carboxylic acid
CFAMM00316755 CHEMBL109206 Bioactive SureCN14203762

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27514 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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