CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8774
Family Name Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [5-(oxan-4-ylmethyl)-[1,3]dioxolo[4,5-f]indol-7-yl]-(2,2,3,3-tetramethylcyclopropyl)methanone family
No. of Seeds 4 No. of Other Members 4
Family Centroid CFAMM00390422 Functional Category Bioactive
Superfamily Prostaglandin D2 receptor and 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Binder Superfamily
Class Class 2976

Cousin Family NamesSeedsMembers
DNA Binder Primaquine Family 3 245
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Phospholipase A2, membrane associated Inhibitor Varespladib Fa... 37 190
Hepatocyte growth factor receptor and Vascular endothelial gro... 28 178
Multidrug resistance protein Inhibitor Tariquidar Family 3 60
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor GSK2... 15 18
Vascular endothelial growth factor receptor 2 Ligand E 7080 Fa... 7 17
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 4 42
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Platelet-derived growth factor receptor alpha and Platelet-der... 2 17
Platelet-derived growth factor receptor alpha and Platelet-der... 2 9
Platelet-derived growth factor receptor beta and Epidermal gro... 3 7
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand WIN-5... 12 52
Serine/threonine-protein kinase Chk1 Inhibitor A-432411 Family 4 70
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(furan-3-... 3 44
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 24 50
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Acetylcholinesterase Inhibitor Lysicamine Family 2 8
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
Disintegrin and metalloproteinase domain-containing protein 17... 14 9
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 2 30
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 1 18
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 391
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 3 5
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 9 12
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 8 32
Vascular endothelial growth factor receptor 2 and Aurora kinas... 3 3
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 4 14
Histamine H3 receptor and Cytochrome P450 2D6 ligand AGN-PC-00... 18 32
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 8 12
Ferritin light chain and Ras-related protein Rab-9A inhibitor ... 1 11
Acetylcholinesterase and Cholinesterase inhibitor (2Z)-5-metho... 4 23
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(1,3-... 2 9
Cellular tumor antigen p53 inhibitor CHEMBL1395699 family 1 30
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 1
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 5 2
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 2
Vascular endothelial growth factor receptor 2 and Vascular end... 2 52
Peroxisome proliferator-activated receptor alpha and Peroxisom... 1 4
Cytosolic phospholipase A2 inhibitor AGN-PC-00BH8R family 6 13
Potassium voltage-gated channel subfamily H member 2 and 5-hyd... 2 2
Seprase and Prolyl endopeptidase inhibitor N-[2-[(2S)-2-cyanop... 1 3
Vascular endothelial growth factor receptor 2 ligand N-(4-chlo... 11 7
Mast/stem cell growth factor receptor Kit and Serine/threonine... 11 29
Serine/threonine-protein kinase Chk1 inhibitor SureCN4854955 f... 2 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 4 1
Vascular endothelial growth factor receptor 2 ligand 6-(6,7-di... 4 0
Vascular endothelial growth factor receptor 2 and Cytochrome P... 2 1
Vascular endothelial growth factor receptor 2 ligand N-(4-chlo... 4 4
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 1 3
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 3 3
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 7 1
Platelet-activating factor receptor ligand N,N-dimethyl-6-phen... 12 18
Platelet-activating factor receptor ligand 5,6-dimethoxy-N,N-d... 2 3
Substance-P receptor ligand (4R)-N-[(2R)-1-[benzyl(methyl)amin... 1 4
Cannabinoid receptor 1 ligand (4-hydroxynaphthalen-1-yl)-[1-(2... 2 0
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
CGMP-dependent protein kinase inhibitor AGN-PC-075IHL family 2 8
Macrophage colony-stimulating factor 1 receptor ligand 4-(2,3-... 12 7
Macrophage colony-stimulating factor 1 receptor ligand 4-(3-ch... 5 4
Ras guanyl-releasing protein 3 and Protein kinase C alpha type... 2 6
Cyclin-dependent kinase 4 and Cyclin-dependent kinase 2 inhibi... 1 12
Inositol monophosphatase 1 and Prelamin-A/C inhibitor GNF-Pf-3... 1 5
Mitogen-activated protein kinase 14 inhibitor SureCN4508019 fa... 1 0
Gamma-aminobutyric acid receptor subunit pi and Gamma-aminobut... 2 10


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00390422 CHEMBL272868 Bioactive [5-(oxan-4-ylmethyl)-[1,3]dioxolo[4,5-f]indol-7-yl]-(2,2,3,3-tetramethylcyclopropyl)methanone
CFAMM00390420 CHEMBL1836186 Bioactive AGN-PC-0BFW19
CFAMM00390419 CHEMBL270125 Bioactive SureCN2075566
CFAMM00390418 CHEMBL270987 Bioactive SureCN2077179

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27043 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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