CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8776
Family Name Neuropeptide Y receptor type 5 ligand N-[5-(4,5-dihydro-[1]benzothiepino[5,4-d][1,3]thiazol-2-ylamino)pentyl]ethanesulfonamide family
No. of Seeds 8 No. of Other Members 9
Family Centroid CFAMM00390444 Functional Category Bioactive
Superfamily Reverse transcriptase Inhibitor 1-benzothiazol-2-yl-3-phenethyl-thiourea Superfamily
Class Class 2319

Cousin Family NamesSeedsMembers
Cytochrome P450 26A1 Inhibitor Rambazole Family 7 77
C-C chemokine receptor type 4 Ligand N-(naphthalen-1-yl)-4-neo... 5 78
Reverse transcriptase Inhibitor 1-benzothiazol-2-yl-3-phenethy... 2 19
Neuropeptide Y receptor type 5 ligand N-[[(1S,5R)-3-(1-phenyle... 5 1
Neuropeptide S receptor and Niemann-Pick C1 protein ligand CHE... 1 1
Neuropeptide Y receptor type 5 ligand N-[5-[(9-fluoro-5,6-dihy... 7 7
Neuropeptide Y receptor type 5 ligand N-[5-[(4-thiophen-3-yl-1... 1 4
Neuropeptide Y receptor type 5 ligand 1-[4-[[(9-fluoro-5,6-dih... 11 0
Kynurenine 3-monooxygenase inhibitor 4-amino-N-[4-(3-nitrophen... 2 2


External ID

Functional Category

Molecule Name

CFAMM00390442 CHEMBL1836316 Bioactive N-[[4-(4,5-dihydro-[1]benzothiepino[5,4-d][1,3]thiazol-2-ylamino)cyclohexyl]methyl]thiophene-2-sulfonamide
CFAMM00390435 CHEMBL83830 Bioactive 2-[[4-[(dimethylsulfamoylamino)methyl]cyclohexyl]amino]-9-fluoro-4,5-dihydro-[1]benzothiepino[5,4-d][1,3]thiazole
CFAMM00390432 CHEMBL1836330 Bioactive N-[5-[(9-fluoro-4,5-dihydro-[1]benzothiepino[5,4-d][1,3]thiazol-2-yl)amino]pentyl]methanesulfonamide
CFAMM00390431 CHEMBL1909722 Bioactive N-[5-(4,5-dihydro-[1]benzothiepino[5,4-d][1,3]thiazol-2-ylamino)pentyl]propane-2-sulfonamide
CFAMM00390445 CHEMBL1836323 Bioactive N-[5-(4,5-dihydro-[1]benzothiepino[5,4-d][1,3]thiazol-2-ylamino)pentyl]methanesulfonamide
CFAMM00390444 CHEMBL1836324 Bioactive N-[5-(4,5-dihydro-[1]benzothiepino[5,4-d][1,3]thiazol-2-ylamino)pentyl]ethanesulfonamide
CFAMM00390437 CHEMBL1836317 Bioactive N-[[4-(4,5-dihydro-[1]benzothiepino[5,4-d][1,3]thiazol-2-ylamino)cyclohexyl]methyl]methanesulfonamide
CFAMM00390436 CHEMBL1836318 Bioactive N-[[4-(4,5-dihydro-[1]benzothiepino[5,4-d][1,3]thiazol-2-ylamino)cyclohexyl]methyl]ethanesulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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