CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8801
Family Name Cysteinyl leukotriene receptor 1 ligand SureCN7008285 family
No. of Seeds 12 No. of Other Members 97
Family Centroid CFAMM00390619 Functional Category Bioactive
Superfamily Cysteinyl leukotriene receptor 1 and Type-1 angiotensin II receptor Binder Superfamily
Class Class 3578

Cousin Family NamesSeedsMembers
Cysteinyl leukotriene receptor 1 Ligand Pranlukast Family 21 72
Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031... 3 206
Melanin-concentrating hormone receptor 1 Ligand 8-sec-butoxy-q... 30 39
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(2-methyl... 7 27
Cysteinyl leukotriene receptor 1 ligand SureCN7808360 family 4 11
Leukotriene B4 receptor 1 ligand AGN-PC-075N6M family 2 4
Leukotriene B4 receptor 1 ligand SureCN8987110 family 8 20
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 2 13
Cysteinyl leukotriene receptor 1 ligand 2-[[3-[[3-methoxy-5-(2... 8 0
Cysteinyl leukotriene receptor 1 ligand 7-[[3-(quinolin-2-ylme... 7 5
Cysteinyl leukotriene receptor 1 ligand AGN-PC-03MOKX family 2 2
Arachidonate 5-lipoxygenase-activating protein inhibitor 2-[[4... 5 0
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 4 4
Type-1 angiotensin II receptor ligand methyl 2-methyl-6-propyl... 7 10
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 7 1
Type-1 angiotensin II receptor ligand 2-ethyl-6-methoxy-N-[[4-... 2 0
Type-1B angiotensin II receptor ligand AGN-PC-040VXR family 6 15
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 4 0
Type-1 angiotensin II receptor ligand 2-[(2-methyl-5,6,7,8-tet... 5 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 3
Gonadotropin-releasing hormone receptor ligand 1-[2-(3,5-dimet... 1 0
Cysteinyl leukotriene receptor 2 and Cysteinyl leukotriene rec... 1 3


External ID

Functional Category

Molecule Name

CFAMM00390655 CHEMBL18597 Bioactive SureCN6088661
CFAMM00390674 CHEMBL276136 Bioactive SureCN6089355
CFAMM00390619 CHEMBL18956 Bioactive SureCN7008285
CFAMM00390618 CHEMBL275866 Bioactive SureCN10421449
CFAMM00390678 CHEMBL93991 Bioactive SureCN10607946
CFAMM00390571 CHEMBL18918 Bioactive SureCN6088514
CFAMM00390597 CHEMBL18833 Bioactive SureCN7010321
CFAMM00390623 CHEMBL18816 Bioactive SureCN6090157
CFAMM00390664 CHEMBL95799 Bioactive SureCN8987246
CFAMM00390676 CHEMBL18518 Bioactive RG-12525
CFAMM00390621 CHEMBL18381 Bioactive SureCN9821174
CFAMM00390675 CHEMBL18699 Bioactive SureCN6089752

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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