CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8802
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor AGN-PC-075DN3 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00390681 Functional Category Bioactive
Superfamily Farnesyltransferase beta subunit, putative Inhibitor BMS214662 Superfamily
Class Class 853

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Vascular endothe... 6 34
Farnesyltransferase beta subunit, putative Inhibitor BMS214662... 11 65
PF-4217903 family 14 65
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Metabotropic glutamate receptor 5 Ligand 3-(1-pyridin-2-yl-1h-... 3 6
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-phen... 8 11
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Protein farnesyltransferase subunit beta Inhibitor BMS-316810 ... 11 18
Farnesyltransferase beta subunit, putative and Protein farnesy... 12 4
Neuronal acetylcholine receptor subunit alpha-7 and Potassium ... 4 7
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Glycogen synthase kinase-3 beta and Dual specificity protein k... 4 5
Tyrosine-protein kinase JAK2 inhibitor N-tert-butyl-3-[2-[3-fl... 4 14
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 11
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 0
TGF-beta receptor type-1 and TGF-beta receptor type-2 ligand S... 2 2
Protein farnesyltransferase alpha subunit and Protein farnesyl... 5 0
Protein farnesyltransferase alpha subunit and Protein farnesyl... 2 0
Bombesin receptor subtype-3 and Nuclear receptor subfamily 1 g... 3 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[6-... 3 3
Cyclin-dependent kinase 2 inhibitor Imidazo[1,2-b]pyridazine d... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00390681 CHEMBL183810 Bioactive AGN-PC-075DN3

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

25251 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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