CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8811
Family Name Disintegrin and metalloproteinase domain-containing protein 17 inhibitor (2R,5R)-1-[4-[(2-ethylphenyl)methoxy]phenyl]sulfonyl-N,5-dihydroxypiperidine-2-carboxamide family
No. of Seeds 25 No. of Other Members 5
Family Centroid CFAMM00390733 Functional Category Bioactive
Superfamily Disintegrin and metalloproteinase domain-containing protein 17 and Interstitial collagenase Binder Superfamily
Class Class 3248

Cousin Family NamesSeedsMembers
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 15 129
Disintegrin and metalloproteinase domain-containing protein 17... 82 411
Disintegrin and metalloproteinase domain-containing protein 17... 25 33
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 7
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 16
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 4-benzy... 10 32
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 13
Disintegrin and metalloproteinase domain-containing protein 17... 2 8
Disintegrin and metalloproteinase domain-containing protein 17... 10 39
Collagenase 3 and Interstitial collagenase inhibitor N-hydroxy... 8 4
Collagenase 3 and Interstitial collagenase inhibitor AGN-PC-01... 10 1
Cathepsin K inhibitor SureCN6578603 family 1 3
Collagenase 3 and Interstitial collagenase inhibitor (1R,5S)-3... 2 1
Collagenase 3 and Interstitial collagenase inhibitor (3S)-3-[[... 5 1
Pol polyprotein inhibitor morpholinone scaffold 1 family 5 29
72 kDa type IV collagenase and Collagenase 3 inhibitor N-hydro... 3 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 4-acety... 9 4
Collagenase 3 and Matrix metalloproteinase-9 inhibitor (4R)-N-... 13 4
Collagenase 3 and Stromelysin-1 inhibitor 1-N-benzyl-3-N-hydro... 7 15
Matrix metalloproteinase-9 and Collagenase 3 inhibitor N-hydro... 2 1
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 7 12
Neutrophil collagenase and Stromelysin-1 inhibitor 7-[[(2S)-2-... 10 9
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-075O... 14 27
Collagenase 3 and 72 kDa type IV collagenase inhibitor (5R)-N-... 7 0
Neutrophil collagenase inhibitor (3R)-2-[4-[4-(dimethylamino)p... 2 4
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-044L... 2 0
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R)-1-... 25 6
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4S)... 7 1
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R,4S)... 3 0
Matrix metalloproteinase-15 and Matrix metalloproteinase-16 in... 1 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4Z)... 17 0
Stromelysin-1 and Matrix metalloproteinase-9 inhibitor AGN-PC-... 26 12
Disintegrin and metalloproteinase domain-containing protein 17... 4 2
Macrophage metalloelastase and 72 kDa type IV collagenase inhi... 7 4
Disintegrin and metalloproteinase domain-containing protein 17... 6 12
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 2
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-... 4 6
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-... 2 0
Collagenase 3 and Neutrophil collagenase inhibitor (3R)-1-hydr... 1 0
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 3 0
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 3 0
72 kDa type IV collagenase and Disintegrin and metalloproteina... 5 1
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzy... 13 3
Disintegrin and metalloproteinase domain-containing protein 17... 2 0
Pol polyprotein inhibitor N-[2-Hydroxy-2-(8-Isopropyl-6,9-Diox... 7 6
Disintegrin and metalloproteinase domain-containing protein 17... 13 1
Neutrophil elastase inhibitor 2-[3-[(4-methoxyphenyl)sulfonyla... 1 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzy... 6 2
Neutrophil collagenase and Interstitial collagenase inhibitor ... 3 0
Collagenase 3 and Disintegrin and metalloproteinase domain-con... 2 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-acety... 6 7
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 3 2
72 kDa type IV collagenase and Collagenase 3 inhibitor 2-[[2-(... 2 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(3S)-2... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00390747 CHEMBL96771 Bioactive AGN-PC-074PRK
CFAMM00390740 CHEMBL58577 Bioactive (2R,3R,4R,5R)-N,3,4,5-tetrahydroxy-1-(4-phenylmethoxyphenyl)sulfonylpiperidine-2-carboxamide
CFAMM00390733 CHEMBL29069 Bioactive (2R,5R)-1-[4-[(2-ethylphenyl)methoxy]phenyl]sulfonyl-N,5-dihydroxypiperidine-2-carboxamide
CFAMM00390739 CHEMBL27965 Bioactive (2R,5R)-N,5-dihydroxy-1-[4-[[2-(trifluoromethyl)phenyl]methoxy]phenyl]sulfonylpiperidine-2-carboxamide
CFAMM00390732 CHEMBL191030 Bioactive (2R,5R)-1-[4-[(5-fluoro-2-methylphenyl)methoxy]phenyl]sulfonyl-N,5-dihydroxypiperidine-2-carboxamide
CFAMM00390745 CHEMBL31294 Bioactive (2R,5R)-N,5-dihydroxy-1-[4-[(2-methylphenyl)methoxy]phenyl]sulfonylpiperidine-2-carboxamide
CFAMM00390738 CHEMBL435102 Bioactive (2R,3S)-3-ethyl-1-[4-[(4-fluorophenyl)methoxy]phenyl]sulfonyl-N,3-dihydroxypiperidine-2-carboxamide
CFAMM00390744 CHEMBL282584 Bioactive (2R,5R)-N,5-dihydroxy-1-[4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]sulfonylpiperidine-2-carboxamide
CFAMM00390731 CHEMBL281920 Bioactive (2R,4S)-N,4-dihydroxy-1-(4-phenylmethoxyphenyl)sulfonylpiperidine-2-carboxamide
CFAMM00390743 CHEMBL285272 Bioactive (2R,5R)-N,5-dihydroxy-1-[4-[(2-iodophenyl)methoxy]phenyl]sulfonylpiperidine-2-carboxamide
CFAMM00390736 CHEMBL28358 Bioactive (2R,4S)-N,4-dihydroxy-1-[4-[(2-methylphenyl)methoxy]phenyl]sulfonylpiperidine-2-carboxamide
CFAMM00390742 CHEMBL29007 Bioactive (2R,5R)-N,5-dihydroxy-1-(4-phenylmethoxyphenyl)sulfonylpiperidine-2-carboxamide
CFAMM00390735 CHEMBL363126 Bioactive (2R,3R)-1-[4-[(3-fluoro-2-methylphenyl)methoxy]phenyl]sulfonyl-N,3-dihydroxy-3-methylpiperidine-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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