CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8815
Family Name Melatonin receptor type 1B and Melatonin receptor type 1A ligand N-[(3S)-1-[2-(4-phenylbutyl)-1-benzofuran-4-yl]pyrrolidin-3-yl]butanamide family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00230174 Functional Category Bioactive with Natural Product
Superfamily Muscarinic acetylcholine receptor M2 and Muscarinic acetylcholine receptor M4 Binder Superfamily 2
Class Class 1685

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
D(2) dopamine receptor Ligand Aplindore Fumarate Family 2 30
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Amine oxidase [flavin-containing] A Inhibitor Ethyl 4-(2-oxo-2... 4 117
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 11 20
Macrophage migration inhibitory factor Inhibitor Benzofuran-2-... 5 67
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Lanosterol synthase inhibitor SureCN7685733 family 1 3
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 3 13
C-C chemokine receptor type 3 ligand SureCN6705515 family 2 16
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 49 8
Survival motor neuron protein and DNA-(apurinic or apyrimidini... 1 5
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 3 1
Trace amine-associated receptor 1 ligand EPPTB family 4 9
Histamine H3 receptor ligand N-[[2-[2-[(2R)-2-methylpyrrolidin... 4 1
Histamine H3 receptor ligand 3-[[2-[2-[(2R)-2-methylpyrrolidin... 3 1
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 3 6
Motilin receptor ligand SureCN14564469 family 1 6
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand CHEMB... 6 3
Delta-type opioid receptor and Kappa-type opioid receptor liga... 5 0
Neuropeptide Y receptor type 1 ligand 1-(1-benzofuran-6-yl)-3-... 1 1
Dual specificity mitogen-activated protein kinase kinase 1 inh... 3 0
Progesterone receptor ligand AGN-PC-00PB7I family 1 5
NP (s)-3-(2,5-dioxo-2,3,4,5-tetrahydro-1h-benzo[e][1,4]diazepi... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00390781 CHEMBL186977 Bioactive N-[(3S)-1-[2-(4-phenylbutyl)-1-benzofuran-4-yl]pyrrolidin-3-yl]propanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27521 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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